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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMX2
All Species:
18.18
Human Site:
Y265
Identified Species:
36.36
UniProt:
A2RU54
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2RU54
NP_005510.1
273
29598
Y265
N
L
S
A
L
P
L
Y
N
L
Y
N
K
L
D
Chimpanzee
Pan troglodytes
XP_508091
273
29596
Y265
N
L
S
A
L
P
L
Y
N
L
Y
N
K
L
D
Rhesus Macaque
Macaca mulatta
XP_001105231
273
29541
Y265
N
L
S
A
L
P
L
Y
N
L
Y
N
K
L
D
Dog
Lupus familis
XP_544055
273
29473
Y265
N
L
S
A
L
P
L
Y
N
L
Y
N
K
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P43687
273
29616
Y265
N
L
S
A
L
P
L
Y
N
L
Y
N
K
L
D
Rat
Rattus norvegicus
P63156
327
35117
L294
P
P
A
L
Q
R
P
L
V
P
R
I
L
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517986
237
25439
R230
P
S
A
M
P
F
L
R
P
Q
R
P
G
L
V
Chicken
Gallus gallus
O57601
308
33768
P297
H
P
V
Y
Y
S
H
P
S
V
T
S
V
P
L
Frog
Xenopus laevis
Q8JJ64
306
34004
H294
P
H
P
V
Y
Y
S
H
P
V
V
T
S
V
P
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
P286
H
P
V
Y
Y
S
H
P
I
V
T
S
V
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
P584
A
A
R
N
T
S
P
P
R
P
P
L
S
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26656
405
44721
P369
T
G
S
S
L
H
S
P
N
I
L
P
F
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.8
94.8
N.A.
93.7
28.4
N.A.
39.1
37.9
37.5
37
N.A.
24.6
N.A.
N.A.
29.1
Protein Similarity:
100
99.6
97.8
95.2
N.A.
94.8
39.1
N.A.
51.2
53.5
50
50.8
N.A.
32
N.A.
N.A.
40.7
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
13.3
0
0
0
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
26.6
20
20
N.A.
0
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
42
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
17
9
0
0
0
9
17
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
9
9
0
9
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
42
0
0
% K
% Leu:
0
42
0
9
50
0
50
9
0
42
9
9
9
50
25
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
42
0
0
9
0
0
0
0
50
0
0
42
0
0
0
% N
% Pro:
25
25
9
0
9
42
17
34
17
17
9
17
0
25
9
% P
% Gln:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
9
0
9
9
0
17
0
0
0
0
% R
% Ser:
0
9
50
9
0
25
17
0
9
0
0
17
17
9
0
% S
% Thr:
9
0
0
0
9
0
0
0
0
0
17
9
0
0
0
% T
% Val:
0
0
17
9
0
0
0
0
9
25
9
0
17
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
25
9
0
42
0
0
42
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _