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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DENND3
All Species:
21.52
Human Site:
S445
Identified Species:
67.62
UniProt:
A2RUS2
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2RUS2
NP_055772.2
1198
135890
S445
R
I
N
G
M
L
L
S
P
R
R
P
T
V
E
Chimpanzee
Pan troglodytes
XP_519983
1219
138212
S466
R
I
N
G
M
L
L
S
P
R
R
P
T
V
E
Rhesus Macaque
Macaca mulatta
XP_001082457
1423
159644
S670
R
I
N
G
T
L
V
S
P
R
R
P
T
V
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
A2RT67
1274
143870
S527
R
I
D
R
M
L
I
S
P
R
R
P
T
V
E
Rat
Rattus norvegicus
XP_001072997
1278
143662
S527
R
I
D
R
M
L
I
S
P
R
R
P
T
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513673
1294
147210
S541
R
I
S
V
M
L
V
S
P
R
R
P
T
M
E
Chicken
Gallus gallus
XP_418419
1270
145696
N518
Q
S
E
E
D
R
F
N
L
M
F
R
A
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338419
1268
144940
K508
R
S
E
T
R
R
L
K
I
M
T
E
S
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
77.1
N.A.
N.A.
74.7
73.6
N.A.
68
62.9
N.A.
49.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.7
79.5
N.A.
N.A.
82.5
82.1
N.A.
78.9
76.6
N.A.
68.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
N.A.
N.A.
80
80
N.A.
73.3
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
93.3
93.3
N.A.
93.3
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
25
0
13
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
25
13
0
0
0
0
0
0
0
13
0
0
75
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
13
0
0
0
0
% F
% Gly:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
75
0
0
0
0
25
0
13
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
75
38
0
13
0
0
0
0
0
0
% L
% Met:
0
0
0
0
63
0
0
0
0
25
0
0
0
13
0
% M
% Asn:
0
0
38
0
0
0
0
13
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
75
0
0
75
0
25
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
88
0
0
25
13
25
0
0
0
75
75
13
0
0
25
% R
% Ser:
0
25
13
0
0
0
0
75
0
0
0
0
13
0
0
% S
% Thr:
0
0
0
13
13
0
0
0
0
0
13
0
75
0
0
% T
% Val:
0
0
0
13
0
0
25
0
0
0
0
0
0
63
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _