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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DENND3 All Species: 30
Human Site: Y82 Identified Species: 94.29
UniProt: A2RUS2 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A2RUS2 NP_055772.2 1198 135890 Y82 T Y G V V A Q Y Y R P L H D E
Chimpanzee Pan troglodytes XP_519983 1219 138212 Y82 T Y G V V A Q Y Y R P L H D D
Rhesus Macaque Macaca mulatta XP_001082457 1423 159644 Y300 T Y G V V A Q Y Y R P L H D E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus A2RT67 1274 143870 Y160 T Y G V V A Q Y Y R P L H D E
Rat Rattus norvegicus XP_001072997 1278 143662 Y160 T Y G V V A Q Y Y R P L H D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513673 1294 147210 Y171 T Y G V V A Q Y Y R P V Q D E
Chicken Gallus gallus XP_418419 1270 145696 Y154 T Y G V V A Q Y Y Q P M Q D G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001338419 1268 144940 Y151 T H G V V A Q Y C R P V Q Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 77.1 N.A. N.A. 74.7 73.6 N.A. 68 62.9 N.A. 49.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.7 79.5 N.A. N.A. 82.5 82.1 N.A. 78.9 76.6 N.A. 68.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 N.A. N.A. 100 100 N.A. 86.6 73.3 N.A. 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 93.3 86.6 N.A. 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 88 25 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 13 % G
% His: 0 13 0 0 0 0 0 0 0 0 0 0 63 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 63 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 100 0 0 13 0 0 38 13 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 88 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 100 100 0 0 0 0 0 0 25 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 88 0 0 0 0 0 100 88 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _