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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PION
All Species:
12.73
Human Site:
S107
Identified Species:
40
UniProt:
A4D1B5
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4D1B5
NP_059135.2
854
97802
S107
E
R
T
L
L
A
A
S
L
V
Q
S
T
K
E
Chimpanzee
Pan troglodytes
XP_527798
977
110421
S233
E
R
T
L
L
A
A
S
L
V
Q
S
T
K
E
Rhesus Macaque
Macaca mulatta
XP_001083448
854
98076
S107
E
R
T
L
L
A
A
S
L
V
Q
S
T
K
E
Dog
Lupus familis
XP_533110
808
92555
H90
L
T
L
L
V
E
I
H
P
V
N
N
V
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCV3
858
98675
S103
E
R
T
V
L
A
A
S
F
I
Q
Y
T
T
E
Rat
Rattus norvegicus
NP_001101315
622
71504
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923138
670
76993
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24118
915
102881
V94
S
V
T
L
L
S
F
V
E
K
T
E
G
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85
96
73.5
N.A.
75.1
53.9
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
21.2
N.A.
N.A.
N.A.
Protein Similarity:
100
85.4
97.7
80.6
N.A.
84.7
61.1
N.A.
N.A.
N.A.
N.A.
47
N.A.
39
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
20
N.A.
66.6
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
80
0
N.A.
N.A.
N.A.
N.A.
0
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
50
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
0
0
0
0
13
0
0
13
0
0
13
0
0
50
% E
% Phe:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
13
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
13
0
0
0
63
0
% K
% Leu:
13
0
13
63
63
0
0
0
38
0
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
13
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% Q
% Arg:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
0
0
0
0
13
0
50
0
0
0
38
0
0
0
% S
% Thr:
0
13
63
0
0
0
0
0
0
0
13
0
50
13
0
% T
% Val:
0
13
0
13
13
0
0
13
0
50
0
0
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _