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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
12.73
Human Site:
S251
Identified Species:
23.33
UniProt:
A4D1F6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4D1F6
NP_001155000.1
860
98035
S251
N
Y
I
E
N
F
P
S
D
L
E
C
L
G
N
Chimpanzee
Pan troglodytes
XP_527815
860
98224
T251
N
Y
I
E
N
F
P
T
D
L
E
C
L
G
N
Rhesus Macaque
Macaca mulatta
XP_001101596
863
97942
S254
N
Y
I
E
N
F
P
S
D
L
E
C
L
G
N
Dog
Lupus familis
XP_539413
971
110401
S349
N
C
I
E
N
F
P
S
G
L
K
S
L
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0R9
853
97166
D268
N
M
L
T
Y
I
P
D
S
L
S
S
L
K
N
Rat
Rattus norvegicus
Q6AYI5
582
64902
A28
A
K
E
R
E
K
E
A
K
A
S
G
G
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521360
735
81466
V182
G
Q
E
Q
P
F
R
V
N
H
D
D
K
D
L
Chicken
Gallus gallus
Q5F4C4
529
59144
Frog
Xenopus laevis
Q8AVI4
577
64082
A24
T
K
E
R
E
K
E
A
K
A
V
G
P
V
K
Zebra Danio
Brachydanio rerio
Q1L8Y7
561
62677
D8
M
S
S
T
L
G
K
D
K
D
S
K
E
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396017
561
62921
W8
M
K
K
S
N
K
Y
W
T
G
V
G
N
I
S
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZG8
1045
115404
I278
E
N
Q
L
S
G
E
I
P
P
E
I
G
N
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
92.6
59
N.A.
65.6
25
N.A.
37.4
23.4
25.9
24
N.A.
N.A.
22.5
23.9
N.A.
Protein Similarity:
100
99
93.7
67.3
N.A.
79.3
41.1
N.A.
52.5
40.3
40
39.6
N.A.
N.A.
39
39
N.A.
P-Site Identity:
100
93.3
100
73.3
N.A.
33.3
0
N.A.
6.6
0
0
0
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
100
100
100
80
N.A.
40
6.6
N.A.
26.6
0
6.6
0
N.A.
N.A.
13.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
16
0
16
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
24
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
16
24
8
8
8
0
8
0
% D
% Glu:
8
0
24
31
16
0
24
0
0
0
31
0
8
0
8
% E
% Phe:
0
0
0
0
0
39
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
16
0
0
8
8
0
24
16
31
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
31
0
0
8
0
8
0
0
0
8
0
8
0
% I
% Lys:
0
24
8
0
0
24
8
0
24
0
8
8
8
8
8
% K
% Leu:
0
0
8
8
8
0
0
0
0
39
0
0
39
0
8
% L
% Met:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
39
8
0
0
39
0
0
0
8
0
0
0
8
8
39
% N
% Pro:
0
0
0
0
8
0
39
0
8
8
0
0
8
0
0
% P
% Gln:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
16
0
0
8
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
8
8
8
0
0
24
8
0
24
16
0
0
8
% S
% Thr:
8
0
0
16
0
0
0
8
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
0
0
16
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
24
0
0
8
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _