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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
4.85
Human Site:
T281
Identified Species:
8.89
UniProt:
A4D1F6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4D1F6
NP_001155000.1
860
98035
T281
D
T
L
P
S
L
K
T
L
R
V
L
N
L
E
Chimpanzee
Pan troglodytes
XP_527815
860
98224
N281
D
T
L
P
S
L
K
N
L
R
V
L
N
L
E
Rhesus Macaque
Macaca mulatta
XP_001101596
863
97942
Y284
D
T
L
P
S
L
K
Y
L
R
V
L
N
L
E
Dog
Lupus familis
XP_539413
971
110401
N379
D
T
L
S
G
L
K
N
L
K
V
L
N
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0R9
853
97166
K298
K
S
L
C
F
L
P
K
L
N
S
L
N
L
T
Rat
Rattus norvegicus
Q6AYI5
582
64902
S58
K
D
G
K
K
E
S
S
A
A
Q
P
G
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521360
735
81466
P212
N
S
I
R
G
F
P
P
N
L
D
S
L
S
G
Chicken
Gallus gallus
Q5F4C4
529
59144
Frog
Xenopus laevis
Q8AVI4
577
64082
G54
E
G
K
R
D
P
V
G
A
Q
A
G
V
A
F
Zebra Danio
Brachydanio rerio
Q1L8Y7
561
62677
G38
D
G
K
K
D
T
S
G
A
S
P
A
V
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396017
561
62921
A38
C
N
V
Y
G
Y
R
A
Q
E
N
T
L
V
L
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
K35
L
S
N
F
A
R
N
K
A
R
H
S
L
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZG8
1045
115404
N308
P
I
P
S
T
L
G
N
I
K
T
L
A
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
92.6
59
N.A.
65.6
25
N.A.
37.4
23.4
25.9
24
N.A.
N.A.
22.5
23.9
N.A.
Protein Similarity:
100
99
93.7
67.3
N.A.
79.3
41.1
N.A.
52.5
40.3
40
39.6
N.A.
N.A.
39
39
N.A.
P-Site Identity:
100
93.3
93.3
73.3
N.A.
40
0
N.A.
0
0
0
6.6
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
100
93.3
93.3
80
N.A.
46.6
13.3
N.A.
20
0
13.3
6.6
N.A.
N.A.
20
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
8
31
8
8
8
8
16
8
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
8
0
0
16
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
8
0
0
0
0
8
0
0
0
8
0
0
0
0
39
% E
% Phe:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
16
% F
% Gly:
0
16
8
0
24
0
8
16
0
0
0
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
16
0
16
16
8
0
31
16
0
16
0
0
0
0
0
% K
% Leu:
8
0
39
0
0
47
0
0
39
8
0
47
24
39
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
0
0
0
8
24
8
8
8
0
39
0
0
% N
% Pro:
8
0
8
24
0
8
16
8
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
8
0
0
0
0
% Q
% Arg:
0
0
0
16
0
8
8
0
0
31
0
0
0
0
0
% R
% Ser:
0
24
0
16
24
0
16
8
0
8
8
16
0
16
0
% S
% Thr:
0
31
0
0
8
8
0
8
0
0
8
8
0
0
8
% T
% Val:
0
0
8
0
0
0
8
0
0
0
31
0
16
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _