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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRIFIN
All Species:
11.52
Human Site:
S73
Identified Species:
36.19
UniProt:
A4D1Z8
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4D1Z8
NP_006140
148
16319
S73
W
G
P
E
Q
V
S
S
I
F
P
L
A
P
G
Chimpanzee
Pan troglodytes
XP_001148447
304
33598
V172
S
V
S
L
Q
V
L
V
M
A
P
A
P
G
C
Rhesus Macaque
Macaca mulatta
XP_001084043
324
36188
P94
E
E
R
K
R
S
M
P
F
K
K
G
A
A
F
Dog
Lupus familis
XP_547010
144
16026
S73
W
G
Q
E
E
V
S
S
V
F
P
L
V
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1U0
144
15952
S73
W
G
Q
E
E
V
S
S
I
F
P
L
T
L
G
Rat
Rattus norvegicus
O88644
144
15820
S73
W
G
Q
E
E
V
S
S
V
F
P
L
T
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082394
315
35881
T90
K
W
G
W
E
E
K
T
Y
Q
M
P
F
T
K
Zebra Danio
Brachydanio rerio
Q6DGJ1
139
16307
R66
C
N
S
Y
M
A
N
R
W
G
Q
E
E
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.3
20
74.3
N.A.
70.9
72.9
N.A.
N.A.
N.A.
20
34.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
30.9
29.3
81.7
N.A.
80.4
81
N.A.
N.A.
N.A.
30.1
58.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
6.6
66.6
N.A.
73.3
66.6
N.A.
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
20
80
N.A.
80
80
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
0
0
0
13
0
13
25
13
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
13
13
0
50
50
13
0
0
0
0
0
13
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
13
50
0
0
13
0
13
% F
% Gly:
0
50
13
0
0
0
0
0
0
13
0
13
0
13
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% I
% Lys:
13
0
0
13
0
0
13
0
0
13
13
0
0
0
13
% K
% Leu:
0
0
0
13
0
0
13
0
0
0
0
50
0
38
0
% L
% Met:
0
0
0
0
13
0
13
0
13
0
13
0
0
0
0
% M
% Asn:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
0
0
0
13
0
0
63
13
13
13
0
% P
% Gln:
0
0
38
0
25
0
0
0
0
13
13
0
0
0
0
% Q
% Arg:
0
0
13
0
13
0
0
13
0
0
0
0
0
13
0
% R
% Ser:
13
0
25
0
0
13
50
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
13
0
0
0
0
25
13
0
% T
% Val:
0
13
0
0
0
63
0
13
25
0
0
0
13
0
0
% V
% Trp:
50
13
0
13
0
0
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
0
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _