KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRID2IP
All Species:
5.15
Human Site:
T246
Identified Species:
16.19
UniProt:
A4D2P6
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4D2P6
NP_001138590.1
1211
132276
T246
P
E
R
L
L
V
S
T
R
A
S
A
P
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851432
1053
115808
G140
W
I
E
S
V
L
P
G
S
P
A
D
N
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0QWG9
1203
132002
T235
P
E
R
L
L
V
S
T
R
A
S
A
A
P
R
Rat
Rattus norvegicus
NP_001099380
1022
112159
V109
T
L
R
G
H
G
P
V
W
I
E
S
V
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506252
1002
109665
A89
V
R
R
Y
E
A
V
A
A
S
I
R
A
C
R
Chicken
Gallus gallus
XP_425245
1230
136176
A270
R
L
L
V
S
T
R
A
S
S
V
P
R
S
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6ZM86
1009
113610
T95
V
S
G
V
N
Q
R
T
I
R
V
Y
R
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785700
1336
149352
K265
L
L
D
T
P
T
E
K
K
L
F
E
D
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
82
N.A.
90.6
78.5
N.A.
29.3
69.7
N.A.
44
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
N.A.
N.A.
83.7
N.A.
94.2
81
N.A.
42.3
78.9
N.A.
55.6
N.A.
N.A.
N.A.
N.A.
36.9
P-Site Identity:
100
N.A.
N.A.
0
N.A.
93.3
6.6
N.A.
13.3
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
93.3
13.3
N.A.
20
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
0
25
13
25
13
25
25
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
0
13
13
0
0
% D
% Glu:
0
25
13
0
13
0
13
0
0
0
13
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% F
% Gly:
0
0
13
13
0
13
0
13
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
13
% H
% Ile:
0
13
0
0
0
0
0
0
13
13
13
0
0
13
0
% I
% Lys:
0
0
0
0
0
0
0
13
13
0
0
0
0
0
13
% K
% Leu:
13
38
13
25
25
13
0
0
0
13
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
0
0
0
0
0
13
0
0
% N
% Pro:
25
0
0
0
13
0
25
0
0
13
0
13
13
25
13
% P
% Gln:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
13
50
0
0
0
25
0
25
13
0
13
25
0
50
% R
% Ser:
0
13
0
13
13
0
25
0
25
25
25
13
0
13
13
% S
% Thr:
13
0
0
13
0
25
0
38
0
0
0
0
0
0
0
% T
% Val:
25
0
0
25
13
25
13
13
0
0
25
0
13
0
0
% V
% Trp:
13
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _