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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB5
All Species:
8.48
Human Site:
S108
Identified Species:
23.33
UniProt:
A4FU69
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4FU69
NP_001138525.1
1503
173419
S108
L
D
E
T
E
L
K
S
K
P
E
H
T
W
K
Chimpanzee
Pan troglodytes
XP_001136207
1504
172984
S109
L
D
E
T
G
L
K
S
K
P
E
H
T
W
K
Rhesus Macaque
Macaca mulatta
XP_001108289
1530
176637
S138
L
D
E
T
E
L
K
S
K
L
E
Q
P
W
K
Dog
Lupus familis
XP_537754
1313
151973
K53
D
P
T
A
L
N
S
K
L
E
Q
P
W
K
K
Cat
Felis silvestris
Mouse
Mus musculus
A0JP43
1406
159917
L101
A
G
M
R
K
Q
A
L
E
E
Q
F
N
E
W
Rat
Rattus norvegicus
XP_001080780
1359
155572
Q99
K
V
A
T
M
R
K
Q
A
L
E
E
Q
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510006
1362
154354
Y101
V
T
L
D
T
R
A
Y
L
L
D
K
L
L
P
Chicken
Gallus gallus
XP_415833
1210
136630
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176624
1517
166978
K116
K
E
R
R
E
S
K
K
Q
R
V
K
D
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
90.5
63
N.A.
47.1
45.8
N.A.
43.7
35.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.1
93.5
72.2
N.A.
62.6
61.1
N.A.
58.6
51
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
93.3
80
6.6
N.A.
0
20
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
80
13.3
N.A.
20
26.6
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
12
0
0
23
0
12
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
34
0
12
0
0
0
0
0
0
12
0
12
0
0
% D
% Glu:
0
12
34
0
34
0
0
0
12
23
45
12
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% F
% Gly:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
23
0
0
0
12
0
56
23
34
0
0
23
0
12
56
% K
% Leu:
34
0
12
0
12
34
0
12
23
34
0
0
12
12
0
% L
% Met:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
12
% N
% Pro:
0
12
0
0
0
0
0
0
0
23
0
12
12
0
12
% P
% Gln:
0
0
0
0
0
12
0
12
12
0
23
12
12
0
0
% Q
% Arg:
0
0
12
23
0
23
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
12
12
34
0
0
0
0
0
0
0
% S
% Thr:
0
12
12
45
12
0
0
0
0
0
0
0
23
0
0
% T
% Val:
12
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
34
12
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _