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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB5
All Species:
12.73
Human Site:
S420
Identified Species:
35
UniProt:
A4FU69
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4FU69
NP_001138525.1
1503
173419
S420
L
E
L
F
Y
D
H
S
S
Q
M
L
R
S
L
Chimpanzee
Pan troglodytes
XP_001136207
1504
172984
S421
L
E
L
F
Y
D
H
S
S
Q
M
L
R
S
L
Rhesus Macaque
Macaca mulatta
XP_001108289
1530
176637
S450
L
E
L
F
Y
D
H
S
S
Q
M
L
R
S
L
Dog
Lupus familis
XP_537754
1313
151973
S296
E
F
I
E
Y
V
S
S
Y
V
A
D
F
K
N
Cat
Felis silvestris
Mouse
Mus musculus
A0JP43
1406
159917
S344
A
E
Q
G
S
R
R
S
S
A
V
E
Q
T
Q
Rat
Rattus norvegicus
XP_001080780
1359
155572
V342
Q
T
Q
Q
R
G
S
V
A
Q
Q
G
S
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510006
1362
154354
N344
R
T
L
S
L
L
E
N
F
Y
D
S
S
P
A
Chicken
Gallus gallus
XP_415833
1210
136630
T193
R
M
K
S
E
A
K
T
K
R
K
E
R
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176624
1517
166978
V408
F
E
N
F
W
E
N
V
P
W
S
I
K
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
90.5
63
N.A.
47.1
45.8
N.A.
43.7
35.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.1
93.5
72.2
N.A.
62.6
61.1
N.A.
58.6
51
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
100
13.3
N.A.
20
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
40
13.3
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
12
0
0
12
12
12
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
34
0
0
0
0
12
12
0
0
0
% D
% Glu:
12
56
0
12
12
12
12
0
0
0
0
23
0
12
0
% E
% Phe:
12
12
0
45
0
0
0
0
12
0
0
0
12
0
0
% F
% Gly:
0
0
0
12
0
12
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
12
0
0
0
12
0
12
0
12
0
12
12
0
% K
% Leu:
34
0
45
0
12
12
0
0
0
0
0
34
0
0
34
% L
% Met:
0
12
0
0
0
0
0
0
0
0
34
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
12
12
0
0
0
0
0
0
12
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% P
% Gln:
12
0
23
12
0
0
0
0
0
45
12
0
12
0
23
% Q
% Arg:
23
0
0
0
12
12
12
0
0
12
0
0
45
23
12
% R
% Ser:
0
0
0
23
12
0
23
56
45
0
12
12
23
34
0
% S
% Thr:
0
23
0
0
0
0
0
12
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
12
0
23
0
12
12
0
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
45
0
0
0
12
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _