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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB5
All Species:
6.97
Human Site:
S522
Identified Species:
19.17
UniProt:
A4FU69
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4FU69
NP_001138525.1
1503
173419
S522
E
Q
G
P
Q
R
I
S
I
E
E
Q
Q
Q
G
Chimpanzee
Pan troglodytes
XP_001136207
1504
172984
S523
E
Q
G
P
Q
R
I
S
T
E
E
Q
Q
Q
G
Rhesus Macaque
Macaca mulatta
XP_001108289
1530
176637
Q549
V
T
A
E
Q
G
P
Q
R
I
S
T
E
E
Q
Dog
Lupus familis
XP_537754
1313
151973
D394
D
L
P
E
F
W
G
D
M
D
N
Q
K
H
I
Cat
Felis silvestris
Mouse
Mus musculus
A0JP43
1406
159917
S445
E
Q
G
S
R
R
S
S
A
M
E
Q
E
P
Q
Rat
Rattus norvegicus
XP_001080780
1359
155572
G440
Q
R
R
K
S
F
V
G
D
S
S
T
S
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510006
1362
154354
G442
A
S
L
T
S
I
T
G
D
G
Q
Q
E
E
V
Chicken
Gallus gallus
XP_415833
1210
136630
D291
Y
T
E
N
F
P
N
D
A
F
Q
E
V
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176624
1517
166978
E510
G
D
G
P
A
V
G
E
G
E
G
S
K
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
90.5
63
N.A.
47.1
45.8
N.A.
43.7
35.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
28.7
Protein Similarity:
100
99.1
93.5
72.2
N.A.
62.6
61.1
N.A.
58.6
51
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
93.3
6.6
6.6
N.A.
46.6
0
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
93.3
20
33.3
N.A.
60
20
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
12
0
0
0
23
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
0
0
0
23
23
12
0
0
0
12
0
% D
% Glu:
34
0
12
23
0
0
0
12
0
34
34
12
34
23
23
% E
% Phe:
0
0
0
0
23
12
0
0
0
12
0
0
0
0
0
% F
% Gly:
12
0
45
0
0
12
23
23
12
12
12
0
0
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
12
23
0
12
12
0
0
0
0
12
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
0
0
23
0
12
% K
% Leu:
0
12
12
0
0
0
0
0
0
0
0
0
0
23
0
% L
% Met:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
12
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
12
34
0
12
12
0
0
0
0
0
0
12
0
% P
% Gln:
12
34
0
0
34
0
0
12
0
0
23
56
23
23
23
% Q
% Arg:
0
12
12
0
12
34
0
0
12
0
0
0
0
0
0
% R
% Ser:
0
12
0
12
23
0
12
34
0
12
23
12
12
0
0
% S
% Thr:
0
23
0
12
0
0
12
0
12
0
0
23
0
0
0
% T
% Val:
12
0
0
0
0
12
12
0
0
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _