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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFCAB5 All Species: 13.64
Human Site: T1068 Identified Species: 37.5
UniProt: A4FU69 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A4FU69 NP_001138525.1 1503 173419 T1068 D M K G I S F T V V D E G K P
Chimpanzee Pan troglodytes XP_001136207 1504 172984 T1069 D M K G I S F T V V D E G K P
Rhesus Macaque Macaca mulatta XP_001108289 1530 176637 T1095 D M K G I S F T V V D E G K P
Dog Lupus familis XP_537754 1313 151973 Q918 S F L A L P L Q D A Y M R I F
Cat Felis silvestris
Mouse Mus musculus A0JP43 1406 159917 T972 D M K G I S F T V V D E G K P
Rat Rattus norvegicus XP_001080780 1359 155572 P964 N G S F L A L P L Q D A Y M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510006 1362 154354 D966 L N K V L Y R D M K G I S F A
Chicken Gallus gallus XP_415833 1210 136630 E815 W N Q D R P A E Q R R G S F L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001176624 1517 166978 E1067 D G H T R S Y E E R I R G Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 90.5 63 N.A. 47.1 45.8 N.A. 43.7 35.9 N.A. N.A. N.A. N.A. N.A. N.A. 28.7
Protein Similarity: 100 99.1 93.5 72.2 N.A. 62.6 61.1 N.A. 58.6 51 N.A. N.A. N.A. N.A. N.A. N.A. 49.1
P-Site Identity: 100 100 100 0 N.A. 100 6.6 N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 6.6 N.A. 100 33.3 N.A. 20 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 12 12 0 0 12 0 12 0 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 56 0 0 12 0 0 0 12 12 0 56 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 23 12 0 0 45 0 0 0 % E
% Phe: 0 12 0 12 0 0 45 0 0 0 0 0 0 23 12 % F
% Gly: 0 23 0 45 0 0 0 0 0 0 12 12 56 0 0 % G
% His: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 45 0 0 0 0 0 12 12 0 12 0 % I
% Lys: 0 0 56 0 0 0 0 0 0 12 0 0 0 45 0 % K
% Leu: 12 0 12 0 34 0 23 0 12 0 0 0 0 0 12 % L
% Met: 0 45 0 0 0 0 0 0 12 0 0 12 0 12 0 % M
% Asn: 12 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 23 0 12 0 0 0 0 0 0 45 % P
% Gln: 0 0 12 0 0 0 0 12 12 12 0 0 0 12 0 % Q
% Arg: 0 0 0 0 23 0 12 0 0 23 12 12 12 0 12 % R
% Ser: 12 0 12 0 0 56 0 0 0 0 0 0 23 0 0 % S
% Thr: 0 0 0 12 0 0 0 45 0 0 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 0 0 45 45 0 0 0 0 0 % V
% Trp: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 12 12 0 0 0 12 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _