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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EME2
All Species:
8.18
Human Site:
S121
Identified Species:
25.71
UniProt:
A4GXA9
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4GXA9
NP_001010865.1
379
41207
S121
S
L
R
W
T
R
A
S
P
D
P
C
P
R
S
Chimpanzee
Pan troglodytes
XP_523262
379
41295
S121
S
L
R
W
T
R
A
S
P
D
P
C
P
R
S
Rhesus Macaque
Macaca mulatta
XP_001118625
365
39381
S119
N
G
K
W
G
C
P
S
R
S
A
D
E
Q
E
Dog
Lupus familis
XP_547192
255
27737
W29
Y
L
Q
Y
E
S
L
W
S
H
Q
P
S
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q56A04
373
41064
R115
S
L
Q
W
N
V
V
R
P
D
P
A
P
S
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511003
588
63487
A301
A
L
Q
A
T
E
C
A
C
E
I
E
A
Q
T
Chicken
Gallus gallus
XP_414715
409
45620
M137
S
I
T
W
R
R
N
M
P
S
I
P
S
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_707096
556
61769
S272
S
V
C
W
A
R
R
S
P
C
P
Q
S
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
78.6
32.9
N.A.
65.4
N.A.
N.A.
25.3
42.2
N.A.
23.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.2
83.6
41.9
N.A.
74.6
N.A.
N.A.
38.2
54.5
N.A.
36.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
46.6
N.A.
N.A.
13.3
26.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
20
N.A.
60
N.A.
N.A.
53.3
33.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
13
13
0
25
13
0
0
13
13
13
13
0
% A
% Cys:
0
0
13
0
0
13
13
0
13
13
0
25
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
38
0
13
0
0
0
% D
% Glu:
0
0
0
0
13
13
0
0
0
13
0
13
13
0
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
13
0
0
0
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
0
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
63
0
0
0
0
13
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
13
0
13
0
0
0
0
0
0
0
13
% N
% Pro:
0
0
0
0
0
0
13
0
63
0
50
25
38
0
13
% P
% Gln:
0
0
38
0
0
0
0
0
0
0
13
13
0
25
0
% Q
% Arg:
0
0
25
0
13
50
13
13
13
0
0
0
0
25
13
% R
% Ser:
63
0
0
0
0
13
0
50
13
25
0
0
38
25
25
% S
% Thr:
0
0
13
0
38
0
0
0
0
0
0
0
0
0
13
% T
% Val:
0
13
0
0
0
13
13
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
75
0
0
0
13
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _