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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4KAP2
All Species:
5.45
Human Site:
S310
Identified Species:
15
UniProt:
A4QPH2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4QPH2
NP_477352
592
66981
S310
E
A
D
G
Q
K
I
S
W
Q
A
A
I
F
K
Chimpanzee
Pan troglodytes
XP_525639
2124
239331
S1867
E
A
N
G
Q
K
I
S
W
Q
A
A
I
F
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKC8
816
91497
P382
D
H
H
V
V
R
V
P
H
T
Q
A
V
V
L
Rat
Rattus norvegicus
O08561
816
91637
P382
D
H
H
V
V
R
V
P
H
T
Q
A
V
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415062
604
68837
C354
L
E
K
E
G
L
R
C
R
S
D
S
I
D
E
Frog
Xenopus laevis
Q6GN16
804
90437
R405
E
T
S
L
V
P
V
R
I
P
E
N
R
I
R
Zebra Danio
Brachydanio rerio
Q49GP3
835
94040
R436
E
T
S
S
V
P
V
R
I
P
E
T
Q
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792265
755
84800
S378
I
L
V
L
A
K
K
S
Q
L
L
A
H
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42339
814
93309
D350
M
Y
K
W
E
M
I
D
V
C
D
A
L
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.5
N.A.
N.A.
N.A.
24.8
25
N.A.
N.A.
62.4
24.5
24
N.A.
N.A.
N.A.
N.A.
31.9
Protein Similarity:
100
24.6
N.A.
N.A.
N.A.
38.7
38.4
N.A.
N.A.
71
38.8
40.1
N.A.
N.A.
N.A.
N.A.
47
P-Site Identity:
100
93.3
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
33.3
33.3
N.A.
N.A.
20
20
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
0
0
12
0
0
0
0
0
23
67
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% C
% Asp:
23
0
12
0
0
0
0
12
0
0
23
0
0
12
0
% D
% Glu:
45
12
0
12
12
0
0
0
0
0
23
0
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% F
% Gly:
0
0
0
23
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
23
23
0
0
0
0
0
23
0
0
0
12
0
0
% H
% Ile:
12
0
0
0
0
0
34
0
23
0
0
0
34
23
0
% I
% Lys:
0
0
23
0
0
34
12
0
0
0
0
0
0
0
23
% K
% Leu:
12
12
0
23
0
12
0
0
0
12
12
0
12
0
45
% L
% Met:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
23
0
23
0
23
0
0
0
0
0
% P
% Gln:
0
0
0
0
23
0
0
0
12
23
23
0
12
12
0
% Q
% Arg:
0
0
0
0
0
23
12
23
12
0
0
0
12
0
23
% R
% Ser:
0
0
23
12
0
0
0
34
0
12
0
12
0
0
0
% S
% Thr:
0
23
0
0
0
0
0
0
0
23
0
12
0
0
0
% T
% Val:
0
0
12
23
45
0
45
0
12
0
0
0
23
23
0
% V
% Trp:
0
0
0
12
0
0
0
0
23
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _