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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4KAP2
All Species:
4.24
Human Site:
S72
Identified Species:
11.67
UniProt:
A4QPH2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.63
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4QPH2
NP_477352
592
66981
S72
S
L
L
Q
R
S
M
S
L
N
I
G
R
A
K
Chimpanzee
Pan troglodytes
XP_525639
2124
239331
S1353
S
L
L
Q
R
S
M
S
L
N
I
G
G
A
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKC8
816
91497
K114
G
V
A
S
G
T
A
K
G
A
R
R
R
R
Q
Rat
Rattus norvegicus
O08561
816
91637
K114
G
V
V
S
G
T
A
K
G
T
R
R
R
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415062
604
68837
F92
A
V
Q
L
P
T
R
F
K
N
T
E
A
I
G
Frog
Xenopus laevis
Q6GN16
804
90437
A84
A
G
D
G
G
S
L
A
N
G
D
T
E
P
K
Zebra Danio
Brachydanio rerio
Q49GP3
835
94040
K93
L
Q
K
V
K
F
L
K
G
D
G
E
V
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792265
755
84800
R101
T
Q
S
V
S
E
L
R
E
D
I
S
I
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42339
814
93309
K89
E
L
I
T
L
S
S
K
Y
R
D
L
T
A
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.5
N.A.
N.A.
N.A.
24.8
25
N.A.
N.A.
62.4
24.5
24
N.A.
N.A.
N.A.
N.A.
31.9
Protein Similarity:
100
24.6
N.A.
N.A.
N.A.
38.7
38.4
N.A.
N.A.
71
38.8
40.1
N.A.
N.A.
N.A.
N.A.
47
P-Site Identity:
100
93.3
N.A.
N.A.
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
N.A.
N.A.
26.6
33.3
N.A.
N.A.
26.6
33.3
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
12
0
0
0
23
12
0
12
0
0
12
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
23
23
0
0
0
0
% D
% Glu:
12
0
0
0
0
12
0
0
12
0
0
23
12
0
0
% E
% Phe:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% F
% Gly:
23
12
0
12
34
0
0
0
34
12
12
23
12
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
34
0
12
12
12
% I
% Lys:
0
0
12
0
12
0
0
45
12
0
0
0
0
0
34
% K
% Leu:
12
34
23
12
12
0
34
0
23
0
0
12
0
12
0
% L
% Met:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
34
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
0
% P
% Gln:
0
23
12
23
0
0
0
0
0
0
0
0
0
0
23
% Q
% Arg:
0
0
0
0
23
0
12
12
0
12
23
23
34
23
0
% R
% Ser:
23
0
12
23
12
45
12
23
0
0
0
12
0
12
12
% S
% Thr:
12
0
0
12
0
34
0
0
0
12
12
12
12
0
0
% T
% Val:
0
34
12
23
0
0
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _