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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4KAP2
All Species:
10.91
Human Site:
Y406
Identified Species:
30
UniProt:
A4QPH2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A4QPH2
NP_477352
592
66981
Y406
T
D
F
G
M
Y
D
Y
F
T
R
Q
Y
G
D
Chimpanzee
Pan troglodytes
XP_525639
2124
239331
F1956
G
D
E
S
T
L
A
F
Q
Q
A
R
Y
N
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKC8
816
91497
Y633
S
Q
L
S
L
L
D
Y
F
L
Q
E
H
G
S
Rat
Rattus norvegicus
O08561
816
91637
Y633
S
Q
L
S
L
L
D
Y
F
L
Q
E
H
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415062
604
68837
Q437
P
D
C
T
S
R
D
Q
L
G
R
Q
T
D
F
Frog
Xenopus laevis
Q6GN16
804
90437
Y621
S
Q
L
S
L
L
H
Y
F
L
Q
E
H
G
S
Zebra Danio
Brachydanio rerio
Q49GP3
835
94040
Y652
S
Q
L
L
L
L
D
Y
F
R
Q
E
H
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792265
755
84800
K506
A
P
F
L
A
R
F
K
V
Q
K
C
G
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42339
814
93309
Q633
R
S
I
T
S
Y
L
Q
K
F
H
P
D
E
H
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.5
N.A.
N.A.
N.A.
24.8
25
N.A.
N.A.
62.4
24.5
24
N.A.
N.A.
N.A.
N.A.
31.9
Protein Similarity:
100
24.6
N.A.
N.A.
N.A.
38.7
38.4
N.A.
N.A.
71
38.8
40.1
N.A.
N.A.
N.A.
N.A.
47
P-Site Identity:
100
13.3
N.A.
N.A.
N.A.
26.6
26.6
N.A.
N.A.
26.6
20
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
N.A.
N.A.
N.A.
60
60
N.A.
N.A.
26.6
53.3
66.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
12
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
34
0
0
0
0
56
0
0
0
0
0
12
12
12
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
45
0
12
0
% E
% Phe:
0
0
23
0
0
0
12
12
56
12
0
0
0
0
23
% F
% Gly:
12
0
0
12
0
0
0
0
0
12
0
0
12
56
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
12
0
45
0
23
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
12
0
12
0
0
0
0
% K
% Leu:
0
0
45
23
45
56
12
0
12
34
0
0
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% N
% Pro:
12
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
45
0
0
0
0
0
23
12
23
45
23
0
0
0
% Q
% Arg:
12
0
0
0
0
23
0
0
0
12
23
12
0
0
0
% R
% Ser:
45
12
0
45
23
0
0
0
0
0
0
0
0
0
34
% S
% Thr:
12
0
0
23
12
0
0
0
0
12
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
23
0
56
0
0
0
0
23
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _