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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLEC18A All Species: 13.33
Human Site: Y259 Identified Species: 41.9
UniProt: A5D8T8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A5D8T8 NP_001129686.1 446 49602 Y259 P P G Y T G R Y C Q V R C S L
Chimpanzee Pan troglodytes XP_001173366 303 33707 E125 H G R F R E E E C S C V C D I
Rhesus Macaque Macaca mulatta XP_001107949 446 49561 Y259 P P G Y T G R Y C Q V R C S L
Dog Lupus familis XP_853065 425 47303 Q240 G Y T G R Y C Q V R C S G Q C
Cat Felis silvestris
Mouse Mus musculus Q7TSQ1 534 58566 Y347 Q P G Y T G R Y C Q V R C S V
Rat Rattus norvegicus NP_001163952 483 52130 P264 P A V E T K A P P S L A T E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518260 538 59967 Y351 P P G Y T G R Y C Q V R C S V
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175890 317 35010 D139 Y N E D Q Y Y D Y D T H S C S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.8 96.4 79.1 N.A. 64.9 24 N.A. 61.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 23.9
Protein Similarity: 100 64.8 97 84.5 N.A. 72 37.8 N.A. 69.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 33.6
P-Site Identity: 100 13.3 100 0 N.A. 86.6 13.3 N.A. 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 26.6 100 6.6 N.A. 93.3 20 N.A. 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 13 0 0 0 0 13 0 0 0 % A
% Cys: 0 0 0 0 0 0 13 0 63 0 25 0 63 13 13 % C
% Asp: 0 0 0 13 0 0 0 13 0 13 0 0 0 13 0 % D
% Glu: 0 0 13 13 0 13 13 13 0 0 0 0 0 13 0 % E
% Phe: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 13 50 13 0 50 0 0 0 0 0 0 13 0 13 % G
% His: 13 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % I
% Lys: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 50 0 0 0 0 0 13 13 0 0 0 0 0 0 % P
% Gln: 13 0 0 0 13 0 0 13 0 50 0 0 0 13 0 % Q
% Arg: 0 0 13 0 25 0 50 0 0 13 0 50 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 25 0 13 13 50 13 % S
% Thr: 0 0 13 0 63 0 0 0 0 0 13 0 13 0 0 % T
% Val: 0 0 13 0 0 0 0 0 13 0 50 13 0 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 13 0 50 0 25 13 50 13 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _