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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS37C
All Species:
29.7
Human Site:
S65
Identified Species:
65.33
UniProt:
A5D8V6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A5D8V6
NP_060436.4
355
38633
S65
G
P
L
E
I
S
R
S
N
L
S
D
R
Y
Q
Chimpanzee
Pan troglodytes
XP_508469
523
57160
S233
G
P
L
E
I
S
R
S
N
L
S
D
K
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001083551
520
56269
S230
G
P
L
E
I
S
R
S
N
L
S
D
K
Y
Q
Dog
Lupus familis
XP_540924
374
40616
S83
G
P
L
E
I
S
R
S
N
L
S
D
K
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R105
352
38434
S65
G
P
L
E
I
S
R
S
N
L
S
D
K
Y
Q
Rat
Rattus norvegicus
NP_001100933
353
38422
S65
G
P
L
E
I
S
R
S
N
L
S
D
K
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514899
391
42738
S65
S
P
L
E
L
G
R
S
D
L
S
D
K
Y
R
Chicken
Gallus gallus
XP_420953
356
38743
S65
V
P
L
E
T
G
R
S
E
L
S
S
K
Y
E
Frog
Xenopus laevis
NP_001083414
287
32077
L19
S
L
T
Q
L
N
E
L
L
E
D
E
E
K
L
Zebra Danio
Brachydanio rerio
NP_001071253
323
35175
D55
S
L
A
E
Q
N
L
D
M
K
P
R
I
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120612
218
24547
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.9
65.3
81
N.A.
81.9
81.1
N.A.
58.3
58.1
38.5
35.4
N.A.
N.A.
20.8
N.A.
N.A.
Protein Similarity:
100
67.1
66.1
84.7
N.A.
85.6
85
N.A.
68.2
69
50.7
52.3
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
60
53.3
0
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
66.6
26.6
13.3
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
10
0
10
64
0
0
0
% D
% Glu:
0
0
0
82
0
0
10
0
10
10
0
10
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
55
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
64
10
0
% K
% Leu:
0
19
73
0
19
0
10
10
10
73
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
19
0
0
55
0
0
0
0
0
10
% N
% Pro:
0
73
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
55
% Q
% Arg:
0
0
0
0
0
0
73
0
0
0
0
10
10
0
10
% R
% Ser:
28
0
0
0
0
55
0
73
0
0
73
10
0
0
0
% S
% Thr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _