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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSD All Species: 13.33
Human Site: S543 Identified Species: 36.67
UniProt: A5PKW4 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A5PKW4 NP_002770.3 1024 109543 S543 T E R L A L G S T D T L S N G
Chimpanzee Pan troglodytes XP_001147971 1047 116010 T570 T E I L E K E T P E N L S N G
Rhesus Macaque Macaca mulatta XP_001104642 972 103908 F511 P D S F S C V F E A E G G S G
Dog Lupus familis XP_543989 1104 117965 S623 T E R L A L G S T D T L S N G
Cat Felis silvestris
Mouse Mus musculus Q5DTT2 1024 109669 S543 T E R L A L G S T D T L S N G
Rat Rattus norvegicus Q9ESQ7 649 70799 F211 H L G K N N D F S K L V A G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515158 727 79981 K289 L Y N L E G F K H C D V A R Q
Chicken Gallus gallus XP_421634 585 65180 S147 T P L A S N M S E H P L S Q L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_699541 951 106455 A511 N E F S H M V A E E Y L S H F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.4 83 88.3 N.A. 92 59.7 N.A. 40.9 42.2 N.A. 40.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 52.3 83.5 89.4 N.A. 94 61 N.A. 50.2 47.4 N.A. 55.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 46.6 6.6 100 N.A. 100 0 N.A. 6.6 26.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 60 26.6 100 N.A. 100 20 N.A. 20 33.3 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 34 0 0 12 0 12 0 0 23 0 0 % A
% Cys: 0 0 0 0 0 12 0 0 0 12 0 0 0 0 0 % C
% Asp: 0 12 0 0 0 0 12 0 0 34 12 0 0 0 0 % D
% Glu: 0 56 0 0 23 0 12 0 34 23 12 0 0 0 12 % E
% Phe: 0 0 12 12 0 0 12 23 0 0 0 0 0 0 12 % F
% Gly: 0 0 12 0 0 12 34 0 0 0 0 12 12 12 56 % G
% His: 12 0 0 0 12 0 0 0 12 12 0 0 0 12 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 12 0 12 0 12 0 0 0 0 0 % K
% Leu: 12 12 12 56 0 34 0 0 0 0 12 67 0 0 12 % L
% Met: 0 0 0 0 0 12 12 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 12 0 12 23 0 0 0 0 12 0 0 45 0 % N
% Pro: 12 12 0 0 0 0 0 0 12 0 12 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 12 % Q
% Arg: 0 0 34 0 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 0 0 12 12 23 0 0 45 12 0 0 0 67 12 0 % S
% Thr: 56 0 0 0 0 0 0 12 34 0 34 0 0 0 0 % T
% Val: 0 0 0 0 0 0 23 0 0 0 0 23 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _