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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM189
All Species:
26.36
Human Site:
S158
Identified Species:
58
UniProt:
A5PLL7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A5PLL7
NP_001155977.1
270
31136
S158
A
Y
K
F
R
T
H
S
P
E
A
L
E
Q
L
Chimpanzee
Pan troglodytes
XP_001167732
270
30988
S158
A
Y
K
F
R
T
H
S
P
E
A
L
E
Q
L
Rhesus Macaque
Macaca mulatta
XP_001096634
270
30996
S158
A
Y
K
F
R
T
H
S
P
E
A
L
E
Q
L
Dog
Lupus familis
XP_854159
121
14710
I27
E
C
F
V
F
C
L
I
I
F
G
T
F
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q99LQ7
271
31115
S159
A
Y
K
F
R
T
Q
S
P
E
T
L
E
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508210
286
32432
S174
A
Y
K
F
S
T
L
S
P
E
S
V
Q
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001167513
289
33209
T177
A
Y
K
F
M
F
Y
T
P
D
L
I
Y
K
T
Zebra Danio
Brachydanio rerio
NP_001006052
274
31336
S162
A
A
N
F
L
M
L
S
P
A
E
I
Y
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610026
310
35351
T198
A
H
Y
F
Y
I
R
T
P
S
E
I
Q
Q
H
Honey Bee
Apis mellifera
XP_396481
307
35379
P195
T
W
D
F
L
T
L
P
E
S
E
I
Q
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798250
284
32432
S172
T
F
I
L
F
S
S
S
T
E
T
I
Q
Q
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
44
N.A.
92.9
N.A.
N.A.
78.3
N.A.
67.1
68.6
N.A.
50.6
53
N.A.
55.2
Protein Similarity:
100
99.6
99.2
44.4
N.A.
94.8
N.A.
N.A.
82.5
N.A.
76.8
77.7
N.A.
64.1
65.4
N.A.
67.9
P-Site Identity:
100
100
100
0
N.A.
86.6
N.A.
N.A.
66.6
N.A.
33.3
26.6
N.A.
26.6
20
N.A.
20
P-Site Similarity:
100
100
100
0
N.A.
86.6
N.A.
N.A.
86.6
N.A.
66.6
40
N.A.
53.3
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
10
0
0
0
0
0
0
0
10
28
0
0
0
0
% A
% Cys:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
10
55
28
0
37
0
0
% E
% Phe:
0
10
10
82
19
10
0
0
0
10
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
10
0
0
0
0
28
0
0
0
0
0
0
0
19
% H
% Ile:
0
0
10
0
0
10
0
10
10
0
0
46
0
0
0
% I
% Lys:
0
0
55
0
0
0
0
0
0
0
0
0
0
10
10
% K
% Leu:
0
0
0
10
19
0
37
0
0
0
10
37
0
0
46
% L
% Met:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
19
% N
% Pro:
0
0
0
0
0
0
0
10
73
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
37
73
0
% Q
% Arg:
0
0
0
0
37
0
10
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
10
10
10
64
0
19
10
0
0
0
0
% S
% Thr:
19
0
0
0
0
55
0
19
10
0
19
10
0
10
10
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
55
10
0
10
0
10
0
0
0
0
0
19
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _