KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM189
All Species:
40.61
Human Site:
T125
Identified Species:
89.33
UniProt:
A5PLL7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A5PLL7
NP_001155977.1
270
31136
T125
R
E
H
H
I
D
P
T
A
I
T
R
H
D
F
Chimpanzee
Pan troglodytes
XP_001167732
270
30988
T125
R
E
H
H
I
D
P
T
A
I
T
R
H
D
F
Rhesus Macaque
Macaca mulatta
XP_001096634
270
30996
T125
R
E
H
H
I
D
P
T
A
I
T
R
H
D
F
Dog
Lupus familis
XP_854159
121
14710
Cat
Felis silvestris
Mouse
Mus musculus
Q99LQ7
271
31115
T126
R
E
H
H
I
D
P
T
A
I
T
R
H
D
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508210
286
32432
T141
R
E
H
H
I
D
P
T
A
I
T
R
H
D
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001167513
289
33209
T144
R
E
H
H
I
D
P
T
A
I
T
R
H
D
F
Zebra Danio
Brachydanio rerio
NP_001006052
274
31336
T129
R
E
H
H
I
D
P
T
A
I
T
R
H
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610026
310
35351
T165
R
E
H
H
L
D
P
T
S
I
T
R
H
D
F
Honey Bee
Apis mellifera
XP_396481
307
35379
T162
R
E
H
H
I
D
P
T
S
I
T
R
H
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798250
284
32432
T139
R
E
H
H
I
D
P
T
A
I
T
R
H
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
44
N.A.
92.9
N.A.
N.A.
78.3
N.A.
67.1
68.6
N.A.
50.6
53
N.A.
55.2
Protein Similarity:
100
99.6
99.2
44.4
N.A.
94.8
N.A.
N.A.
82.5
N.A.
76.8
77.7
N.A.
64.1
65.4
N.A.
67.9
P-Site Identity:
100
100
100
0
N.A.
100
N.A.
N.A.
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
93.3
P-Site Similarity:
100
100
100
0
N.A.
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
91
0
0
0
0
0
0
0
91
0
% D
% Glu:
0
91
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
91
91
0
0
0
0
0
0
0
0
91
0
0
% H
% Ile:
0
0
0
0
82
0
0
0
0
91
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
91
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
91
0
0
91
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _