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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM189 All Species: 17.27
Human Site: T200 Identified Species: 38
UniProt: A5PLL7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A5PLL7 NP_001155977.1 270 31136 T200 F G L P R W V T L L Q D W H V
Chimpanzee Pan troglodytes XP_001167732 270 30988 T200 F G L P R W V T L L Q D W H V
Rhesus Macaque Macaca mulatta XP_001096634 270 30996 T200 F G L P R W V T L L Q D W H V
Dog Lupus familis XP_854159 121 14710 H69 R K H H R I H H V S P H E T Y
Cat Felis silvestris
Mouse Mus musculus Q99LQ7 271 31115 T201 L G L P Y W V T V L Q D W H V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508210 286 32432 T216 F G L P R W V T F L Q D W H I
Chicken Gallus gallus
Frog Xenopus laevis NP_001167513 289 33209 V219 F G L P G W V V F L Q D W H I
Zebra Danio Brachydanio rerio NP_001006052 274 31336 V204 F G L P R W V V L L Q D C H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610026 310 35351 L240 W G L P R W V L L L Q S C H I
Honey Bee Apis mellifera XP_396481 307 35379 V237 F G L P S W V V W L Q E H R I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798250 284 32432 Q214 F G L P A W V Q F L Q R Y H L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 44 N.A. 92.9 N.A. N.A. 78.3 N.A. 67.1 68.6 N.A. 50.6 53 N.A. 55.2
Protein Similarity: 100 99.6 99.2 44.4 N.A. 94.8 N.A. N.A. 82.5 N.A. 76.8 77.7 N.A. 64.1 65.4 N.A. 67.9
P-Site Identity: 100 100 100 6.6 N.A. 80 N.A. N.A. 86.6 N.A. 73.3 80 N.A. 66.6 53.3 N.A. 60
P-Site Similarity: 100 100 100 13.3 N.A. 86.6 N.A. N.A. 93.3 N.A. 80 86.6 N.A. 80 66.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % E
% Phe: 73 0 0 0 0 0 0 0 28 0 0 0 0 0 0 % F
% Gly: 0 91 0 0 10 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 10 10 0 0 10 10 0 0 0 10 10 82 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 46 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 91 0 0 0 0 10 46 91 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 91 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 91 0 0 0 0 % Q
% Arg: 10 0 0 0 64 0 0 0 0 0 0 10 0 10 0 % R
% Ser: 0 0 0 0 10 0 0 0 0 10 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 46 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 0 0 91 28 19 0 0 0 0 0 37 % V
% Trp: 10 0 0 0 0 91 0 0 10 0 0 0 55 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _