KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF11
All Species:
14.24
Human Site:
S223
Identified Species:
28.48
UniProt:
A6BM72
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6BM72
NP_115821.2
1044
110844
S223
E
E
L
C
P
P
G
S
H
G
A
H
C
E
L
Chimpanzee
Pan troglodytes
XP_001158904
1056
113028
K229
E
D
L
C
P
P
G
K
H
G
P
Q
C
E
Q
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
K229
E
D
L
C
P
P
G
K
H
G
P
Q
C
E
Q
Dog
Lupus familis
XP_544734
1153
122923
S284
E
E
L
C
P
P
G
S
H
G
A
H
C
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80T91
1091
116040
S222
E
E
L
C
P
P
G
S
H
G
A
H
C
E
L
Rat
Rattus norvegicus
O88281
1574
165428
T563
N
E
T
C
P
P
D
T
F
G
K
N
C
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507076
1158
124996
K243
E
D
L
C
P
P
G
K
H
G
S
Q
C
E
E
Chicken
Gallus gallus
XP_413915
1100
119310
T238
A
Q
P
C
P
P
G
T
F
G
I
N
C
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P46530
2437
262289
A569
E
L
D
I
N
E
C
A
S
S
P
C
H
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728660
1031
112996
K222
D
M
R
C
P
D
G
K
H
G
A
Q
C
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
K240
L
N
K
C
E
E
G
K
F
G
A
E
C
K
F
Sea Urchin
Strong. purpuratus
P10079
1064
112055
V237
V
D
G
V
N
G
Y
V
C
N
C
V
P
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
59.8
76.7
N.A.
80.7
27.3
N.A.
58.4
72.4
N.A.
20.6
N.A.
33.7
N.A.
33.4
24.5
Protein Similarity:
100
76.9
71.9
81.1
N.A.
86
37.2
N.A.
71.2
81.3
N.A.
28.8
N.A.
47
N.A.
47.5
38.2
P-Site Identity:
100
66.6
66.6
100
N.A.
100
40
N.A.
66.6
40
N.A.
6.6
N.A.
46.6
N.A.
33.3
0
P-Site Similarity:
100
73.3
73.3
100
N.A.
100
53.3
N.A.
80
60
N.A.
13.3
N.A.
60
N.A.
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
0
0
42
0
0
0
0
% A
% Cys:
0
0
0
84
0
0
9
0
9
0
9
9
84
0
0
% C
% Asp:
9
34
9
0
0
9
9
0
0
0
0
0
0
0
0
% D
% Glu:
59
34
0
0
9
17
0
0
0
0
0
9
0
50
9
% E
% Phe:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
17
% F
% Gly:
0
0
9
0
0
9
75
0
0
84
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
59
0
0
25
9
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
42
0
0
9
0
0
9
0
% K
% Leu:
9
9
50
0
0
0
0
0
0
0
0
0
0
0
25
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
17
0
0
0
0
9
0
17
0
0
0
% N
% Pro:
0
0
9
0
75
67
0
0
0
0
25
0
9
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
34
0
9
34
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
25
9
9
9
0
0
17
9
% S
% Thr:
0
0
9
0
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
9
0
0
9
0
0
0
9
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _