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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEGF11
All Species:
23.03
Human Site:
T527
Identified Species:
46.06
UniProt:
A6BM72
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6BM72
NP_115821.2
1044
110844
T527
E
L
P
C
P
D
G
T
F
G
L
N
C
S
E
Chimpanzee
Pan troglodytes
XP_001158904
1056
113028
T533
E
L
P
C
Q
D
G
T
Y
G
L
N
C
A
E
Rhesus Macaque
Macaca mulatta
XP_001097941
1137
121871
T533
E
L
P
C
Q
D
G
T
Y
G
L
N
C
A
E
Dog
Lupus familis
XP_544734
1153
122923
T588
E
L
P
C
P
D
G
T
F
G
L
N
C
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80T91
1091
116040
T526
E
L
P
C
P
D
G
T
F
G
L
N
C
S
E
Rat
Rattus norvegicus
O88281
1574
165428
L1041
L
Q
A
C
P
P
G
L
Y
G
K
N
C
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507076
1158
124996
S547
E
L
T
C
Q
D
G
S
Y
G
M
N
C
A
E
Chicken
Gallus gallus
XP_413915
1100
119310
R542
D
N
M
C
T
Q
G
R
W
G
P
N
C
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P46530
2437
262289
Q1105
S
C
E
V
A
A
R
Q
Q
G
V
S
V
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728660
1031
112996
K526
E
R
K
C
D
T
G
K
F
G
H
D
C
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XWD6
1111
118785
G551
C
D
I
G
C
P
E
G
S
Y
G
P
G
C
K
Sea Urchin
Strong. purpuratus
P10079
1064
112055
T549
C
T
C
V
P
G
Y
T
G
V
L
C
E
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
59.8
76.7
N.A.
80.7
27.3
N.A.
58.4
72.4
N.A.
20.6
N.A.
33.7
N.A.
33.4
24.5
Protein Similarity:
100
76.9
71.9
81.1
N.A.
86
37.2
N.A.
71.2
81.3
N.A.
28.8
N.A.
47
N.A.
47.5
38.2
P-Site Identity:
100
80
80
100
N.A.
100
40
N.A.
60
40
N.A.
6.6
N.A.
40
N.A.
0
20
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
46.6
N.A.
86.6
53.3
N.A.
26.6
N.A.
60
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
9
0
0
0
0
0
0
0
42
0
% A
% Cys:
17
9
9
75
9
0
0
0
0
0
0
9
75
9
0
% C
% Asp:
9
9
0
0
9
50
0
0
0
0
0
9
0
0
9
% D
% Glu:
59
0
9
0
0
0
9
0
0
0
0
0
9
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
75
9
9
84
9
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
9
0
0
0
0
9
0
0
9
0
0
0
9
% K
% Leu:
9
50
0
0
0
0
0
9
0
0
50
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
67
0
0
0
% N
% Pro:
0
0
42
0
42
17
0
0
0
0
9
9
0
0
0
% P
% Gln:
0
9
0
0
25
9
0
9
9
0
0
0
0
9
9
% Q
% Arg:
0
9
0
0
0
0
9
9
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
0
0
9
9
0
0
9
0
34
0
% S
% Thr:
0
9
9
0
9
9
0
50
0
0
0
0
0
9
0
% T
% Val:
0
0
0
17
0
0
0
0
0
9
9
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
34
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _