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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 4.55
Human Site: S185 Identified Species: 25
UniProt: A6NC78 Number Species: 4
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NC78 XP_001724310 632 71330 S185 G E L E S V L S D V M A T Q K
Chimpanzee Pan troglodytes XP_001162659 632 71523 S185 G E L E S V L S D V M A T Q K
Rhesus Macaque Macaca mulatta XP_001103006 810 92676 L277 I Q E L E R A L S A V C T Q Q
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q921M4 999 113260 K340 L G V E E L Q K K L E M S E L
Rat Rattus norvegicus Q62839 998 112826 K340 L G A E E L Q K K L E M S E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 43.4 N.A. N.A. 31.2 31.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.9 53.4 N.A. N.A. 44.7 44.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 N.A. N.A. 6.6 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 N.A. N.A. 40 33.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 0 20 0 0 20 0 40 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 % D
% Glu: 0 40 20 80 60 0 0 0 0 0 40 0 0 40 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 40 40 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 40 40 0 0 0 0 0 40 % K
% Leu: 40 0 40 20 0 40 40 20 0 40 0 0 0 0 40 % L
% Met: 0 0 0 0 0 0 0 0 0 0 40 40 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 20 0 0 0 0 40 0 0 0 0 0 0 60 20 % Q
% Arg: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 40 0 0 40 20 0 0 0 40 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % T
% Val: 0 0 20 0 0 40 0 0 0 40 20 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _