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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
All Species:
8.48
Human Site:
S458
Identified Species:
46.67
UniProt:
A6NC78
Number Species:
4
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NC78
XP_001724310
632
71330
S458
E
S
R
E
A
M
S
S
F
M
D
H
L
E
E
Chimpanzee
Pan troglodytes
XP_001162659
632
71523
S458
E
N
R
E
A
M
S
S
F
M
D
H
L
E
E
Rhesus Macaque
Macaca mulatta
XP_001103006
810
92676
S633
E
S
Q
E
A
M
S
S
F
M
D
L
P
K
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921M4
999
113260
R808
A
M
E
K
L
Q
S
R
F
L
E
V
M
Q
E
Rat
Rattus norvegicus
Q62839
998
112826
R807
A
M
E
K
L
Q
S
R
F
L
E
V
M
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
43.4
N.A.
N.A.
31.2
31.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.9
53.4
N.A.
N.A.
44.7
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
73.3
N.A.
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
N.A.
N.A.
53.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
0
% D
% Glu:
60
0
40
60
0
0
0
0
0
0
40
0
0
40
100
% E
% Phe:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
40
0
0
0
0
0
0
0
0
0
20
0
% K
% Leu:
0
0
0
0
40
0
0
0
0
40
0
20
40
0
0
% L
% Met:
0
40
0
0
0
60
0
0
0
60
0
0
40
0
0
% M
% Asn:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% P
% Gln:
0
0
20
0
0
40
0
0
0
0
0
0
0
40
0
% Q
% Arg:
0
0
40
0
0
0
0
40
0
0
0
0
0
0
0
% R
% Ser:
0
40
0
0
0
0
100
60
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _