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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM172B All Species: 17.58
Human Site: S254 Identified Species: 35.15
UniProt: A6NC97 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NC97 NP_114431 362 41969 S254 R R R W E V M S K V Y A V A L
Chimpanzee Pan troglodytes XP_001146868 362 41951 S254 R R R W E V M S K V Y A V A L
Rhesus Macaque Macaca mulatta XP_001096765 362 41860 S254 R R R W E V M S K V Y A V A L
Dog Lupus familis XP_851856 474 53890 S336 Q R E A D V K S K V T A V A L
Cat Felis silvestris
Mouse Mus musculus Q3TNH5 417 48054 D310 L M I Q R E A D V K S K V T A
Rat Rattus norvegicus NP_001099871 370 42818 D263 L M I Q R E A D V K S K V T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518938 512 57149 G407 R R R G E V M G K V F A V A L
Chicken Gallus gallus Q5ZK44 416 48335 E309 L M I Q R E T E V K N K V T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T297 415 48190 S309 N R E A E V K S R V R A V A M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95RN0 325 36543 A220 P E S V A I V A H S Y G G S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XW78 313 35293 F208 C L T D S P W F E F P K S C A
Sea Urchin Strong. purpuratus XP_790439 454 51379 T345 S K Q V S A G T Q V H A E T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 96.1 33.1 N.A. 37.4 40.2 N.A. 44.1 36.5 N.A. 40 N.A. 20.7 N.A. 24.8 21.5
Protein Similarity: 100 100 98.3 49.3 N.A. 56.3 61 N.A. 54.4 55.7 N.A. 55.6 N.A. 37.8 N.A. 41.4 36.5
P-Site Identity: 100 100 100 60 N.A. 6.6 6.6 N.A. 80 6.6 N.A. 53.3 N.A. 13.3 N.A. 0 13.3
P-Site Similarity: 100 100 100 73.3 N.A. 6.6 6.6 N.A. 86.6 6.6 N.A. 66.6 N.A. 40 N.A. 6.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 9 9 17 9 0 0 0 59 0 50 34 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 9 9 0 0 17 0 0 0 0 0 0 0 % D
% Glu: 0 9 17 0 42 25 0 9 9 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 9 9 0 0 0 0 % F
% Gly: 0 0 0 9 0 0 9 9 0 0 0 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % H
% Ile: 0 0 25 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 17 0 42 25 0 34 0 0 0 % K
% Leu: 25 9 0 0 0 0 0 0 0 0 0 0 0 0 50 % L
% Met: 0 25 0 0 0 0 34 0 0 0 0 0 0 0 9 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 9 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % P
% Gln: 9 0 9 25 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 34 50 34 0 25 0 0 0 9 0 9 0 0 0 0 % R
% Ser: 9 0 9 0 17 0 0 42 0 9 17 0 9 9 9 % S
% Thr: 0 0 9 0 0 0 9 9 0 0 9 0 0 34 0 % T
% Val: 0 0 0 17 0 50 9 0 25 59 0 0 75 0 0 % V
% Trp: 0 0 0 25 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _