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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM172B All Species: 14.24
Human Site: S312 Identified Species: 28.48
UniProt: A6NC97 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NC97 NP_114431 362 41969 S312 K K E F P M V S A G T E K Y I
Chimpanzee Pan troglodytes XP_001146868 362 41951 S312 K K E F P M V S A G T E K Y I
Rhesus Macaque Macaca mulatta XP_001096765 362 41860 S312 K K E F P M V S A G T E K Y S
Dog Lupus familis XP_851856 474 53890 A393 P D C P R V S A G T L A K S L
Cat Felis silvestris
Mouse Mus musculus Q3TNH5 417 48054 P366 E S M L P D C P R V S A G T D
Rat Rattus norvegicus NP_001099871 370 42818 P319 E S M L P D C P R V S A G T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518938 512 57149 T463 V L K A D C P T V S A G T E K
Chicken Gallus gallus Q5ZK44 416 48335 P365 E S M L P D C P R V S A G T E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T297 415 48190 S365 L N D C P R V S A G T E K H E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95RN0 325 36543 T276 C D W V A S N T P L D T P V S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XW78 313 35293 A264 H E W S S H C A I D A V F H I
Sea Urchin Strong. purpuratus XP_790439 454 51379 T404 E E D D D D G T L E L R K E Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 96.1 33.1 N.A. 37.4 40.2 N.A. 44.1 36.5 N.A. 40 N.A. 20.7 N.A. 24.8 21.5
Protein Similarity: 100 100 98.3 49.3 N.A. 56.3 61 N.A. 54.4 55.7 N.A. 55.6 N.A. 37.8 N.A. 41.4 36.5
P-Site Identity: 100 100 93.3 6.6 N.A. 6.6 6.6 N.A. 0 6.6 N.A. 53.3 N.A. 0 N.A. 6.6 6.6
P-Site Similarity: 100 100 93.3 26.6 N.A. 20 20 N.A. 13.3 20 N.A. 66.6 N.A. 6.6 N.A. 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 17 34 0 17 34 0 0 0 % A
% Cys: 9 0 9 9 0 9 34 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 17 9 17 34 0 0 0 9 9 0 0 0 17 % D
% Glu: 34 17 25 0 0 0 0 0 0 9 0 34 0 17 17 % E
% Phe: 0 0 0 25 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 9 34 0 9 25 0 0 % G
% His: 9 0 0 0 0 9 0 0 0 0 0 0 0 17 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 25 % I
% Lys: 25 25 9 0 0 0 0 0 0 0 0 0 50 0 9 % K
% Leu: 9 9 0 25 0 0 0 0 9 9 17 0 0 0 9 % L
% Met: 0 0 25 0 0 25 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 9 59 0 9 25 9 0 0 0 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 9 9 0 0 25 0 0 9 0 0 0 % R
% Ser: 0 25 0 9 9 9 9 34 0 9 25 0 0 9 17 % S
% Thr: 0 0 0 0 0 0 0 25 0 9 34 9 9 25 0 % T
% Val: 9 0 0 9 0 9 34 0 9 25 0 9 0 9 0 % V
% Trp: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _