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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM172B All Species: 23.94
Human Site: Y43 Identified Species: 47.88
UniProt: A6NC97 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NC97 NP_114431 362 41969 Y43 Q R P F V F N Y Y E N V L E K
Chimpanzee Pan troglodytes XP_001146868 362 41951 Y43 Q R P F V F N Y Y E N V L E K
Rhesus Macaque Macaca mulatta XP_001096765 362 41860 Y43 Q R P F V F N Y Y E N V L E K
Dog Lupus familis XP_851856 474 53890 Y110 G E P F V F N Y R E D L H R W
Cat Felis silvestris
Mouse Mus musculus Q3TNH5 417 48054 Y86 G E P F V F N Y R E D L H R W
Rat Rattus norvegicus NP_001099871 370 42818 E57 K R Y E A L G E I I T R Y V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518938 512 57149 Y202 Q G P Y V F N Y Y K N A L E R
Chicken Gallus gallus Q5ZK44 416 48335 Y86 G E P F V F N Y R E D L H R W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7T297 415 48190 Y84 G E P F V F N Y K E D L H R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95RN0 325 36543 S25 S H S P P P A S N C E E A L I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XW78 313 35293 E13 K L G Y F F D E K G V L K T E
Sea Urchin Strong. purpuratus XP_790439 454 51379 F106 G K P Y E F E F K K G N P M Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 96.1 33.1 N.A. 37.4 40.2 N.A. 44.1 36.5 N.A. 40 N.A. 20.7 N.A. 24.8 21.5
Protein Similarity: 100 100 98.3 49.3 N.A. 56.3 61 N.A. 54.4 55.7 N.A. 55.6 N.A. 37.8 N.A. 41.4 36.5
P-Site Identity: 100 100 100 46.6 N.A. 46.6 6.6 N.A. 66.6 46.6 N.A. 46.6 N.A. 0 N.A. 6.6 13.3
P-Site Similarity: 100 100 100 60 N.A. 60 13.3 N.A. 86.6 60 N.A. 60 N.A. 0 N.A. 40 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 9 0 0 0 0 9 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 0 34 0 0 0 0 % D
% Glu: 0 34 0 9 9 0 9 17 0 59 9 9 0 34 9 % E
% Phe: 0 0 0 59 9 84 0 9 0 0 0 0 0 0 0 % F
% Gly: 42 9 9 0 0 0 9 0 0 9 9 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 34 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 9 % I
% Lys: 17 9 0 0 0 0 0 0 25 17 0 0 9 0 25 % K
% Leu: 0 9 0 0 0 9 0 0 0 0 0 42 34 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 67 0 9 0 34 9 0 0 0 % N
% Pro: 0 0 75 9 9 9 0 0 0 0 0 0 9 0 0 % P
% Gln: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 34 0 0 0 0 0 0 25 0 0 9 0 34 9 % R
% Ser: 9 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 0 9 0 % T
% Val: 0 0 0 0 67 0 0 0 0 0 9 25 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % W
% Tyr: 0 0 9 25 0 0 0 67 34 0 0 0 9 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _