KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VWA3A
All Species:
4.55
Human Site:
Y838
Identified Species:
16.67
UniProt:
A6NCI4
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NCI4
NP_775886.3
1184
134020
Y838
V
G
S
V
Y
K
K
Y
P
Q
G
R
G
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085985
1149
129820
Y810
V
G
S
V
Y
K
K
Y
P
Q
G
R
G
V
R
Dog
Lupus familis
XP_536940
1110
125771
R772
P
Q
G
R
G
I
R
R
V
N
S
S
I
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UVV9
1148
130088
R810
T
Q
G
K
S
I
R
R
I
N
S
S
I
Q
L
Rat
Rattus norvegicus
A1A5Q7
737
83235
V399
K
K
L
G
L
Y
Q
V
L
A
P
N
A
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414917
858
98094
E520
P
E
E
P
S
S
A
E
K
R
R
K
Y
K
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203229
1262
143479
V882
N
K
N
D
V
G
T
V
Y
K
Q
Y
P
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
75.1
N.A.
70.7
47.9
N.A.
N.A.
44.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.2
Protein Similarity:
100
N.A.
87.5
82.8
N.A.
81.7
55.2
N.A.
N.A.
56.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
60.3
P-Site Identity:
100
N.A.
93.3
0
N.A.
0
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
100
6.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
15
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
15
0
0
0
0
15
0
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% F
% Gly:
0
29
29
15
15
15
0
0
0
0
29
0
29
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
29
0
0
15
0
0
0
29
0
0
% I
% Lys:
15
29
0
15
0
29
29
0
15
15
0
15
0
15
0
% K
% Leu:
0
0
15
0
15
0
0
0
15
0
0
0
0
15
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
15
0
0
0
0
0
0
29
0
15
0
0
15
% N
% Pro:
29
0
0
15
0
0
0
0
29
0
15
0
15
0
15
% P
% Gln:
0
29
0
0
0
0
15
0
0
29
15
0
0
29
0
% Q
% Arg:
0
0
0
15
0
0
29
29
0
15
15
29
0
0
29
% R
% Ser:
0
0
29
0
29
15
0
0
0
0
29
29
0
0
0
% S
% Thr:
15
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% T
% Val:
29
0
0
29
15
0
0
29
15
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
29
15
0
29
15
0
0
15
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _