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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 6.67
Human Site: Y245 Identified Species: 29.33
UniProt: A6NCL1 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NCL1 NP_001140158.1 334 37887 Y245 R E D M P I D Y R G D R T T P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001098119 237 26171 K153 A L Q S R D H K R P R L Q P E
Dog Lupus familis XP_850316 365 41611 Y276 R E D L P I N Y G G D G A T P
Cat Felis silvestris
Mouse Mus musculus Q3URY2 333 37739 Y244 P R D L H L D Y V G Q G T H G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512396 346 38611 P257 R A P L N I T P C Q E E E D L
Chicken Gallus gallus
Frog Xenopus laevis NP_001166876 316 34551 S230 A H L T P G H S Q A A T S C S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 23.9 78.9 N.A. 78.7 N.A. N.A. 64.1 N.A. 49.7 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 38 83 N.A. 84.7 N.A. N.A. 72.5 N.A. 62.2 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 6.6 66.6 N.A. 33.3 N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 6.6 80 N.A. 46.6 N.A. N.A. 26.6 N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 17 0 0 0 0 0 0 0 17 17 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 17 0 0 0 0 17 0 % C
% Asp: 0 0 50 0 0 17 34 0 0 0 34 0 0 17 0 % D
% Glu: 0 34 0 0 0 0 0 0 0 0 17 17 17 0 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 17 0 0 17 50 0 34 0 0 17 % G
% His: 0 17 0 0 17 0 34 0 0 0 0 0 0 17 0 % H
% Ile: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % K
% Leu: 0 17 17 50 0 17 0 0 0 0 0 17 0 0 17 % L
% Met: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 17 0 17 0 0 0 0 0 0 0 0 % N
% Pro: 17 0 17 0 50 0 0 17 0 17 0 0 0 17 34 % P
% Gln: 0 0 17 0 0 0 0 0 17 17 17 0 17 0 0 % Q
% Arg: 50 17 0 0 17 0 0 0 34 0 17 17 0 0 0 % R
% Ser: 0 0 0 17 0 0 0 17 0 0 0 0 17 0 17 % S
% Thr: 0 0 0 17 0 0 17 0 0 0 0 17 34 34 0 % T
% Val: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _