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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF222
All Species:
10
Human Site:
S178
Identified Species:
31.43
UniProt:
A6NCQ9
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NCQ9
NP_001140156.1
220
23767
S178
L
A
E
L
S
E
A
S
L
A
P
R
S
A
R
Chimpanzee
Pan troglodytes
XP_523789
220
23738
S178
L
A
E
L
S
E
A
S
L
A
P
R
S
A
R
Rhesus Macaque
Macaca mulatta
XP_001113135
220
23754
S178
L
A
E
L
S
E
A
S
P
A
P
R
S
A
R
Dog
Lupus familis
XP_546612
201
21787
A174
A
F
C
C
R
S
R
A
L
L
L
I
T
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEF8
211
22984
F178
A
P
S
A
T
R
S
F
C
C
R
S
R
A
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519418
151
15642
S124
R
L
G
R
A
R
S
S
A
G
L
G
S
G
P
Chicken
Gallus gallus
XP_425362
210
22795
Q179
A
L
G
L
Q
C
C
Q
S
P
I
A
L
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798828
221
24968
E180
N
K
D
M
F
C
E
E
C
K
V
H
V
C
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.8
80.4
N.A.
84.5
N.A.
N.A.
26.8
46.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
21.7
Protein Similarity:
100
99.5
97.2
84
N.A.
87.7
N.A.
N.A.
36.8
63.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.6
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
N.A.
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
20
N.A.
20
N.A.
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
38
0
13
13
0
38
13
13
38
0
13
0
63
0
% A
% Cys:
0
0
13
13
0
25
13
0
25
13
0
0
0
13
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
38
0
0
38
13
13
0
0
0
0
0
0
0
% E
% Phe:
0
13
0
0
13
0
0
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
25
0
0
0
0
0
0
13
0
13
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
13
13
0
0
0
% I
% Lys:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% K
% Leu:
38
25
0
50
0
0
0
0
38
13
25
0
13
13
13
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
0
0
0
0
0
13
13
38
0
0
0
13
% P
% Gln:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
13
13
25
13
0
0
0
13
38
13
0
38
% R
% Ser:
0
0
13
0
38
13
25
50
13
0
0
13
50
0
0
% S
% Thr:
0
0
0
0
13
0
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
13
0
13
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _