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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-6
All Species:
7.58
Human Site:
S115
Identified Species:
16.67
UniProt:
A6NCS4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NCS4
NP_001129743
301
32121
S115
P
E
R
G
V
G
N
S
G
D
S
V
R
G
G
Chimpanzee
Pan troglodytes
XP_519662
366
38728
S180
P
E
R
G
V
G
N
S
G
D
S
V
R
G
G
Rhesus Macaque
Macaca mulatta
XP_001108914
368
39047
G182
P
E
C
G
V
G
N
G
G
D
S
V
R
G
G
Dog
Lupus familis
XP_543239
342
36276
V158
P
E
R
G
V
G
D
V
G
T
G
A
R
G
D
Cat
Felis silvestris
Mouse
Mus musculus
P43688
289
31578
L106
T
D
R
G
V
G
N
L
S
G
D
M
R
R
G
Rat
Rattus norvegicus
O35767
318
34318
L115
D
K
K
E
L
C
A
L
Q
K
A
V
E
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
S100
E
L
C
A
L
H
K
S
L
E
Q
E
K
R
E
Frog
Xenopus laevis
P42583
299
34079
E107
C
P
L
Q
K
T
L
E
H
D
K
R
E
A
E
Zebra Danio
Brachydanio rerio
Q90481
269
30288
K99
N
S
Q
D
T
S
A
K
S
P
E
P
S
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
N116
Q
P
N
W
Y
N
G
N
D
P
R
F
A
A
A
Sea Urchin
Strong. purpuratus
XP_783123
344
37966
S151
Q
S
A
D
S
K
H
S
S
N
N
I
K
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.1
76.6
56.7
N.A.
59.1
43
N.A.
N.A.
42.1
41.2
35.5
N.A.
N.A.
N.A.
30.2
30.8
Protein Similarity:
100
81.4
77.9
64
N.A.
66.4
52.5
N.A.
N.A.
53.4
53.1
45.8
N.A.
N.A.
N.A.
41.5
43
P-Site Identity:
100
100
86.6
60
N.A.
46.6
6.6
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
86.6
66.6
N.A.
60
33.3
N.A.
N.A.
26.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
19
0
0
0
10
10
10
28
10
% A
% Cys:
10
0
19
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
19
0
0
10
0
10
37
10
0
0
0
28
% D
% Glu:
10
37
0
10
0
0
0
10
0
10
10
10
19
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
46
0
46
10
10
37
10
10
0
0
37
37
% G
% His:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
10
0
10
10
10
10
0
10
10
0
19
0
0
% K
% Leu:
0
10
10
0
19
0
10
19
10
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
10
0
0
10
37
10
0
10
10
0
0
0
0
% N
% Pro:
37
19
0
0
0
0
0
0
0
19
0
10
0
0
0
% P
% Gln:
19
0
10
10
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
0
37
0
0
0
0
0
0
0
10
10
46
28
0
% R
% Ser:
0
19
0
0
10
10
0
37
28
0
28
0
10
0
10
% S
% Thr:
10
0
0
0
10
10
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
46
0
0
10
0
0
0
37
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _