KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-6
All Species:
8.48
Human Site:
S37
Identified Species:
18.67
UniProt:
A6NCS4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NCS4
NP_001129743
301
32121
S37
P
H
P
R
V
R
K
S
P
E
N
F
Q
Y
L
Chimpanzee
Pan troglodytes
XP_519662
366
38728
S102
P
H
P
R
V
R
K
S
P
E
N
F
Q
Y
L
Rhesus Macaque
Macaca mulatta
XP_001108914
368
39047
S104
P
H
P
G
M
R
K
S
S
E
N
F
Q
Y
L
Dog
Lupus familis
XP_543239
342
36276
I55
S
Q
K
Q
E
Q
W
I
P
P
P
W
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P43688
289
31578
N37
S
Q
W
E
L
H
R
N
P
V
K
P
R
Y
L
Rat
Rattus norvegicus
O35767
318
34318
A38
D
L
S
A
R
L
E
A
T
L
A
P
A
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
C37
M
E
L
S
S
P
S
C
M
L
A
T
F
K
Q
Frog
Xenopus laevis
P42583
299
34079
N37
D
I
T
S
R
L
E
N
S
S
C
M
L
S
T
Zebra Danio
Brachydanio rerio
Q90481
269
30288
G37
G
T
E
E
D
T
E
G
S
E
A
T
K
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
P54
S
V
N
S
I
L
S
P
L
E
S
L
V
R
V
Sea Urchin
Strong. purpuratus
XP_783123
344
37966
L49
T
A
G
Y
Q
Q
G
L
P
M
D
S
S
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.1
76.6
56.7
N.A.
59.1
43
N.A.
N.A.
42.1
41.2
35.5
N.A.
N.A.
N.A.
30.2
30.8
Protein Similarity:
100
81.4
77.9
64
N.A.
66.4
52.5
N.A.
N.A.
53.4
53.1
45.8
N.A.
N.A.
N.A.
41.5
43
P-Site Identity:
100
100
80
13.3
N.A.
20
0
N.A.
N.A.
0
0
6.6
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
86.6
40
N.A.
46.6
13.3
N.A.
N.A.
0
13.3
20
N.A.
N.A.
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
10
0
0
28
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% C
% Asp:
19
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
10
10
19
10
0
28
0
0
46
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
28
10
0
0
% F
% Gly:
10
0
10
10
0
0
10
10
0
0
0
0
0
0
0
% G
% His:
0
28
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
28
0
0
0
10
0
10
10
0
% K
% Leu:
0
10
10
0
10
28
0
10
10
19
0
10
10
0
46
% L
% Met:
10
0
0
0
10
0
0
0
10
10
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
19
0
0
28
0
0
0
0
% N
% Pro:
28
0
28
0
0
10
0
10
46
10
10
19
0
0
10
% P
% Gln:
0
19
0
10
10
19
0
0
0
0
0
0
28
0
10
% Q
% Arg:
0
0
0
19
19
28
10
0
0
0
0
0
19
10
0
% R
% Ser:
28
0
10
28
10
0
19
28
28
10
10
10
10
19
0
% S
% Thr:
10
10
10
0
0
10
0
0
10
0
0
19
0
19
10
% T
% Val:
0
10
0
0
19
0
0
0
0
10
0
0
10
0
10
% V
% Trp:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
46
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _