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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGP All Species: 33.64
Human Site: T255 Identified Species: 61.67
UniProt: A6NDG6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDG6 NP_001035830.1 321 34006 T255 Y G I N P E R T V M V G D R L
Chimpanzee Pan troglodytes XP_001162359 321 34104 T255 Y G I N P E R T V M V G D R L
Rhesus Macaque Macaca mulatta XP_001084229 453 47893 T387 Y G I N P E R T V M V G D R L
Dog Lupus familis XP_853602 323 34372 T257 Y G I N P E R T V M V G D R L
Cat Felis silvestris
Mouse Mus musculus Q8CHP8 321 34522 T255 Y G I N P E R T V M V G D R L
Rat Rattus norvegicus Q8VD52 309 33096 M229 F S V D P A R M L M V G D R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F4B1 312 32977 T246 F D I D P A R T I M V G D R L
Frog Xenopus laevis Q3B8E3 270 29197 A207 M G A K P E E A L M I G D D I
Zebra Danio Brachydanio rerio Q5BJJ5 262 28527 A199 L N C S P E E A V M I G D D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649015 330 36359 T258 K K I D P S R T L M I G D R A
Honey Bee Apis mellifera XP_393558 307 34121 T240 Y G L N P E R T L M I G D N C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193132 306 34200 T241 F D V N P Q R T I M I G D R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19881 312 34606 C249 F N L D R S K C C M V G D R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 69.7 76.4 N.A. 90.6 44.2 N.A. N.A. 66.3 26.4 28.6 N.A. 38.7 37 N.A. 42.9
Protein Similarity: 100 99 69.7 81.1 N.A. 94 58.8 N.A. N.A. 77.2 44.5 42.3 N.A. 58.7 59.5 N.A. 62.9
P-Site Identity: 100 100 100 100 N.A. 100 53.3 N.A. N.A. 66.6 40 40 N.A. 53.3 66.6 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 80 N.A. N.A. 86.6 60 53.3 N.A. 73.3 86.6 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 16 0 16 0 0 0 0 0 0 16 % A
% Cys: 0 0 8 0 0 0 0 8 8 0 0 0 0 0 8 % C
% Asp: 0 16 0 31 0 0 0 0 0 0 0 0 100 16 0 % D
% Glu: 0 0 0 0 0 62 16 0 0 0 0 0 0 0 0 % E
% Phe: 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 54 0 0 0 0 0 0 0 0 0 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 54 0 0 0 0 0 16 0 39 0 0 0 8 % I
% Lys: 8 8 0 8 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 16 0 0 0 0 0 31 0 0 0 0 0 70 % L
% Met: 8 0 0 0 0 0 0 8 0 100 0 0 0 0 0 % M
% Asn: 0 16 0 54 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 93 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 77 0 0 0 0 0 0 77 0 % R
% Ser: 0 8 0 8 0 16 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 % T
% Val: 0 0 16 0 0 0 0 0 47 0 62 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _