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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGP All Species: 23.94
Human Site: Y178 Identified Species: 43.89
UniProt: A6NDG6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDG6 NP_001035830.1 321 34006 Y178 G F D P H F S Y M K L T K A L
Chimpanzee Pan troglodytes XP_001162359 321 34104 Y178 G F D P H F S Y M K L T K A L
Rhesus Macaque Macaca mulatta XP_001084229 453 47893 Y310 G F D P H F S Y M K L T K A L
Dog Lupus familis XP_853602 323 34372 Y180 G F D P H F S Y M K L T K A V
Cat Felis silvestris
Mouse Mus musculus Q8CHP8 321 34522 Y178 G F D P H F S Y M K L T K A V
Rat Rattus norvegicus Q8VD52 309 33096 F152 G Y D E H F S F A K L T E A C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F4B1 312 32977 Y168 G F D E H F S Y A K L C Q A L
Frog Xenopus laevis Q3B8E3 270 29197 V139 N V N R A F Q V L I N L Q K P
Zebra Danio Brachydanio rerio Q5BJJ5 262 28527 F131 Y Q T L N K A F Q L I L D G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649015 330 36359 F182 G F D E H F S F P K M M K A A
Honey Bee Apis mellifera XP_393558 307 34121 F163 G F D K D F S F P K I V K A V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193132 306 34200 F163 G F D Q Y F S F M K L L K A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19881 312 34606 Y173 G L D T K V N Y H R L A V T L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 69.7 76.4 N.A. 90.6 44.2 N.A. N.A. 66.3 26.4 28.6 N.A. 38.7 37 N.A. 42.9
Protein Similarity: 100 99 69.7 81.1 N.A. 94 58.8 N.A. N.A. 77.2 44.5 42.3 N.A. 58.7 59.5 N.A. 62.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 60 N.A. N.A. 73.3 6.6 0 N.A. 60 53.3 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 80 N.A. N.A. 80 26.6 26.6 N.A. 73.3 73.3 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 8 0 16 0 0 8 0 77 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % C
% Asp: 0 0 85 0 8 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 24 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 70 0 0 0 85 0 39 0 0 0 0 0 0 0 % F
% Gly: 85 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 62 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 16 0 0 0 0 % I
% Lys: 0 0 0 8 8 8 0 0 0 77 0 0 62 8 0 % K
% Leu: 0 8 0 8 0 0 0 0 8 8 70 24 0 0 39 % L
% Met: 0 0 0 0 0 0 0 0 47 0 8 8 0 0 0 % M
% Asn: 8 0 8 0 8 0 8 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 39 0 0 0 0 16 0 0 0 0 0 8 % P
% Gln: 0 8 0 8 0 0 8 0 8 0 0 0 16 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 77 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 8 8 0 0 0 0 0 0 0 47 0 8 0 % T
% Val: 0 8 0 0 0 8 0 8 0 0 0 8 8 0 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 8 0 0 54 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _