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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGP All Species: 30.91
Human Site: Y187 Identified Species: 56.67
UniProt: A6NDG6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDG6 NP_001035830.1 321 34006 Y187 K L T K A L R Y L Q Q P G C L
Chimpanzee Pan troglodytes XP_001162359 321 34104 Y187 K L T K A L R Y L Q Q P G C L
Rhesus Macaque Macaca mulatta XP_001084229 453 47893 Y319 K L T K A L R Y L Q Q P D C L
Dog Lupus familis XP_853602 323 34372 Y189 K L T K A V R Y L Q Q P G C L
Cat Felis silvestris
Mouse Mus musculus Q8CHP8 321 34522 Y187 K L T K A V R Y L Q Q P D C L
Rat Rattus norvegicus Q8VD52 309 33096 H161 K L T E A C A H L R D P D C L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F4B1 312 32977 Y177 K L C Q A L R Y L L R G P D C
Frog Xenopus laevis Q3B8E3 270 29197 L148 I N L Q K P V L I S L G K G R
Zebra Danio Brachydanio rerio Q5BJJ5 262 28527 L140 L I L D G A P L I A I H K A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649015 330 36359 Y191 K M M K A A S Y L N D P E C L
Honey Bee Apis mellifera XP_393558 307 34121 Y172 K I V K A V T Y L N D P N V H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193132 306 34200 Y172 K L L K A A S Y L K R P N S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19881 312 34606 Y182 R L A V T L Q Y L Q K D S V H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 69.7 76.4 N.A. 90.6 44.2 N.A. N.A. 66.3 26.4 28.6 N.A. 38.7 37 N.A. 42.9
Protein Similarity: 100 99 69.7 81.1 N.A. 94 58.8 N.A. N.A. 77.2 44.5 42.3 N.A. 58.7 59.5 N.A. 62.9
P-Site Identity: 100 100 93.3 93.3 N.A. 86.6 53.3 N.A. N.A. 46.6 0 0 N.A. 53.3 40 N.A. 46.6
P-Site Similarity: 100 100 93.3 100 N.A. 93.3 73.3 N.A. N.A. 60 13.3 13.3 N.A. 60 53.3 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 77 24 8 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 8 0 0 8 0 0 0 0 0 0 0 54 8 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 24 8 24 8 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 16 24 8 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 16 % H
% Ile: 8 16 0 0 0 0 0 0 16 0 8 0 0 0 0 % I
% Lys: 77 0 0 62 8 0 0 0 0 8 8 0 16 0 0 % K
% Leu: 8 70 24 0 0 39 0 16 85 8 8 0 0 0 54 % L
% Met: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 16 0 0 16 0 0 % N
% Pro: 0 0 0 0 0 8 8 0 0 0 0 70 8 0 0 % P
% Gln: 0 0 0 16 0 0 8 0 0 47 39 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 47 0 0 8 16 0 0 0 16 % R
% Ser: 0 0 0 0 0 0 16 0 0 8 0 0 8 8 0 % S
% Thr: 0 0 47 0 8 0 8 0 0 0 0 0 0 0 0 % T
% Val: 0 0 8 8 0 24 8 0 0 0 0 0 0 16 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _