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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 15.76
Human Site: S105 Identified Species: 21.67
UniProt: A6NDJ8 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDJ8 NP_940892 181 20210 S105 I G N K S D L S E L R E V S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 S136 I G N K S D L S E L R E V S L
Dog Lupus familis XP_539883 217 24593 W135 I G N K C D L W E K R H V L F
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 A134 I G N K S D L A D F R E V P L
Rat Rattus norvegicus Q53B90 210 23211 A134 I G N K S D L A D L R E V P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977 E79 S D L S E L R E V Q L E D A Q
Chicken Gallus gallus XP_414313 215 23743 S138 I G N K S D L S D L R E V Q L
Frog Xenopus laevis Q32NQ0 213 24055 A133 M G N K S D L A E K R Q I L F
Zebra Danio Brachydanio rerio NP_001038812 208 22961 S131 I G N K C D L S E S R E V P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 E139 V G N K C D L E E Q R E V D F
Honey Bee Apis mellifera XP_624576 219 25203 E138 I G N K C D L E N L R E V E K
Nematode Worm Caenorhab. elegans NP_502576 210 23303 E128 I G T K C D L E D Q R A I E A
Sea Urchin Strong. purpuratus XP_794320 208 23436 E132 L G N K K D L E Q I R E V D Y
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 A126 V G N K C D L A E N R A V D T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 V126 I G N K N D M V E S K V V S T
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 K126 V G N K C D L K D K R V V E Y
Red Bread Mold Neurospora crassa P33723 203 22458 T126 V G N K S D M T D K K V V E Y
Conservation
Percent
Protein Identity: 100 N.A. 65 46.5 N.A. 79.5 80 N.A. 69.6 73 47.4 65.3 N.A. 44.7 44.2 46.6 52.4
Protein Similarity: 100 N.A. 65.4 62.2 N.A. 82.8 83.3 N.A. 79 80.4 63.3 75.4 N.A. 59.3 61.1 59 68.2
P-Site Identity: 100 N.A. 100 60 N.A. 73.3 80 N.A. 6.6 86.6 53.3 80 N.A. 60 66.6 40 53.3
P-Site Similarity: 100 N.A. 100 60 N.A. 86.6 93.3 N.A. 13.3 93.3 80 80 N.A. 66.6 66.6 53.3 73.3
Percent
Protein Identity: N.A. 40.8 N.A. 41.9 39.8 37.9
Protein Similarity: N.A. 58.1 N.A. 59 58.2 57.6
P-Site Identity: N.A. 53.3 N.A. 53.3 46.6 40
P-Site Similarity: N.A. 66.6 N.A. 73.3 60 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 24 0 0 0 12 0 6 6 % A
% Cys: 0 0 0 0 42 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 0 0 95 0 0 36 0 0 0 6 18 0 % D
% Glu: 0 0 0 0 6 0 0 30 48 0 0 59 0 24 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 18 % F
% Gly: 0 95 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % H
% Ile: 59 0 0 0 0 0 0 0 0 6 0 0 12 0 0 % I
% Lys: 0 0 0 95 6 0 0 6 0 24 12 0 0 0 6 % K
% Leu: 6 0 6 0 0 6 83 0 0 30 6 0 0 12 36 % L
% Met: 6 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 89 0 6 0 0 0 6 6 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 18 0 % P
% Gln: 0 0 0 0 0 0 0 0 6 18 0 6 0 6 6 % Q
% Arg: 0 0 0 0 0 0 6 0 0 0 83 0 0 0 0 % R
% Ser: 6 0 0 6 42 0 0 24 0 12 0 0 0 18 0 % S
% Thr: 0 0 6 0 0 0 0 6 0 0 0 0 0 0 12 % T
% Val: 24 0 0 0 0 0 0 6 6 0 0 18 83 0 0 % V
% Trp: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _