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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 6.97
Human Site: S111 Identified Species: 9.58
UniProt: A6NDJ8 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.44
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDJ8 NP_940892 181 20210 S111 L S E L R E V S L A E A Q S L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 S142 L S E L R E V S L A E A Q S L
Dog Lupus familis XP_539883 217 24593 L141 L W E K R H V L F E D A C T L
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 P140 L A D F R E V P L A E A Q S L
Rat Rattus norvegicus Q53B90 210 23211 P140 L A D L R E V P L A E A Q S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977 A85 R E V Q L E D A Q N L A E H Y
Chicken Gallus gallus XP_414313 215 23743 Q144 L S D L R E V Q L E E A Q S L
Frog Xenopus laevis Q32NQ0 213 24055 L139 L A E K R Q I L F E E A C T L
Zebra Danio Brachydanio rerio NP_001038812 208 22961 P137 L S E S R E V P L E D A Q T M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 D145 L E E Q R E V D F E E A R Q M
Honey Bee Apis mellifera XP_624576 219 25203 E144 L E N L R E V E K G E A E A L
Nematode Worm Caenorhab. elegans NP_502576 210 23303 E134 L E D Q R A I E A E E A E M L
Sea Urchin Strong. purpuratus XP_794320 208 23436 D138 L E Q I R E V D Y E D A Q A L
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 D132 L A E N R A V D T S V A Q A Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 S132 M V E S K V V S T E T G R A L
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 E132 L K D K R V V E Y D V A K E F
Red Bread Mold Neurospora crassa P33723 203 22458 E132 M T D K K V V E Y T V A K E F
Conservation
Percent
Protein Identity: 100 N.A. 65 46.5 N.A. 79.5 80 N.A. 69.6 73 47.4 65.3 N.A. 44.7 44.2 46.6 52.4
Protein Similarity: 100 N.A. 65.4 62.2 N.A. 82.8 83.3 N.A. 79 80.4 63.3 75.4 N.A. 59.3 61.1 59 68.2
P-Site Identity: 100 N.A. 100 40 N.A. 73.3 80 N.A. 13.3 80 40 60 N.A. 46.6 53.3 33.3 46.6
P-Site Similarity: 100 N.A. 100 53.3 N.A. 86.6 93.3 N.A. 26.6 86.6 66.6 80 N.A. 60 66.6 53.3 73.3
Percent
Protein Identity: N.A. 40.8 N.A. 41.9 39.8 37.9
Protein Similarity: N.A. 58.1 N.A. 59 58.2 57.6
P-Site Identity: N.A. 40 N.A. 26.6 26.6 13.3
P-Site Similarity: N.A. 60 N.A. 53.3 40 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 0 0 12 0 6 6 24 0 95 0 24 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % C
% Asp: 0 0 36 0 0 0 6 18 0 6 18 0 0 0 0 % D
% Glu: 0 30 48 0 0 59 0 24 0 48 53 0 18 12 0 % E
% Phe: 0 0 0 6 0 0 0 0 18 0 0 0 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 0 0 6 0 6 0 0 0 % G
% His: 0 0 0 0 0 6 0 0 0 0 0 0 0 6 0 % H
% Ile: 0 0 0 6 0 0 12 0 0 0 0 0 0 0 0 % I
% Lys: 0 6 0 24 12 0 0 0 6 0 0 0 12 0 0 % K
% Leu: 83 0 0 30 6 0 0 12 36 0 6 0 0 0 65 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 6 12 % M
% Asn: 0 0 6 6 0 0 0 0 0 6 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 18 0 0 0 0 0 0 0 % P
% Gln: 0 0 6 18 0 6 0 6 6 0 0 0 48 6 0 % Q
% Arg: 6 0 0 0 83 0 0 0 0 0 0 0 12 0 0 % R
% Ser: 0 24 0 12 0 0 0 18 0 6 0 0 0 30 0 % S
% Thr: 0 6 0 0 0 0 0 0 12 6 6 0 0 18 0 % T
% Val: 0 6 6 0 0 18 83 0 0 0 18 0 0 0 0 % V
% Trp: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 18 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _