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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 33.03
Human Site: S135 Identified Species: 45.42
UniProt: A6NDJ8 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDJ8 NP_940892 181 20210 S135 I E T S A K D S S N V E E A F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 S166 I E T S A K D S S N V E E A F
Dog Lupus familis XP_539883 217 24593 S165 L E T S A K E S K N V D E V F
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 S164 I E T S A K D S S N V E E A F
Rat Rattus norvegicus Q53B90 210 23211 S164 I E T S A K D S S N V E E A F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977 E109 A K D S S N V E E A F V K V A
Chicken Gallus gallus XP_414313 215 23743 D168 A I E T S A K D S S N V E E A
Frog Xenopus laevis Q32NQ0 213 24055 S163 L E T S A K E S H N V D E V F
Zebra Danio Brachydanio rerio NP_001038812 208 22961 S161 I E T S A K D S S N V D E A F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 E169 V M E T S A K E N M N V E D A
Honey Bee Apis mellifera XP_624576 219 25203 E168 V V E T S A K E N T N I D S I
Nematode Worm Caenorhab. elegans NP_502576 210 23303 N158 L E T S A K G N V N V D N A F
Sea Urchin Strong. purpuratus XP_794320 208 23436 S162 I E V S A K D S T N I D E T F
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 I156 E T S A K E S I N V E E A F L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 I156 E T S A K D S I N V E Q A F L
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 T156 E T S A L D S T N V E D A F L
Red Bread Mold Neurospora crassa P33723 203 22458 S156 E T S A K N A S N V E Q A F L
Conservation
Percent
Protein Identity: 100 N.A. 65 46.5 N.A. 79.5 80 N.A. 69.6 73 47.4 65.3 N.A. 44.7 44.2 46.6 52.4
Protein Similarity: 100 N.A. 65.4 62.2 N.A. 82.8 83.3 N.A. 79 80.4 63.3 75.4 N.A. 59.3 61.1 59 68.2
P-Site Identity: 100 N.A. 100 66.6 N.A. 100 100 N.A. 6.6 13.3 66.6 93.3 N.A. 6.6 0 60 66.6
P-Site Similarity: 100 N.A. 100 86.6 N.A. 100 100 N.A. 26.6 33.3 86.6 100 N.A. 33.3 40 80 86.6
Percent
Protein Identity: N.A. 40.8 N.A. 41.9 39.8 37.9
Protein Similarity: N.A. 58.1 N.A. 59 58.2 57.6
P-Site Identity: N.A. 6.6 N.A. 0 0 6.6
P-Site Similarity: N.A. 33.3 N.A. 26.6 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 24 53 18 6 0 0 6 0 0 24 36 18 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 6 0 0 12 36 6 0 0 0 36 6 6 0 % D
% Glu: 24 53 18 0 0 6 12 18 6 0 24 30 59 6 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 6 0 0 24 53 % F
% Gly: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % H
% Ile: 36 6 0 0 0 0 0 12 0 0 6 6 0 0 6 % I
% Lys: 0 6 0 0 18 53 18 0 6 0 0 0 6 0 0 % K
% Leu: 18 0 0 0 6 0 0 0 0 0 0 0 0 0 24 % L
% Met: 0 6 0 0 0 0 0 0 0 6 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 6 36 53 18 0 6 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 24 59 24 0 18 53 36 6 0 0 0 6 0 % S
% Thr: 0 24 48 18 0 0 0 6 6 6 0 0 0 6 0 % T
% Val: 12 6 6 0 0 0 6 0 6 24 48 18 0 18 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _