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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 22.42
Human Site: S136 Identified Species: 30.83
UniProt: A6NDJ8 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDJ8 NP_940892 181 20210 S136 E T S A K D S S N V E E A F L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 S167 E T S A K D S S N V E E A F L
Dog Lupus familis XP_539883 217 24593 K166 E T S A K E S K N V D E V F T
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 S165 E T S A K D S S N V E E A F T
Rat Rattus norvegicus Q53B90 210 23211 S165 E T S A K D S S N V E E A F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977 E110 K D S S N V E E A F V K V A T
Chicken Gallus gallus XP_414313 215 23743 S169 I E T S A K D S S N V E E A F
Frog Xenopus laevis Q32NQ0 213 24055 H164 E T S A K E S H N V D E V F L
Zebra Danio Brachydanio rerio NP_001038812 208 22961 S162 E T S A K D S S N V D E A F N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 N170 M E T S A K E N M N V E D A F
Honey Bee Apis mellifera XP_624576 219 25203 N169 V E T S A K E N T N I D S I F
Nematode Worm Caenorhab. elegans NP_502576 210 23303 V159 E T S A K G N V N V D N A F L
Sea Urchin Strong. purpuratus XP_794320 208 23436 T163 E V S A K D S T N I D E T F W
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 N157 T S A K E S I N V E E A F L A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 N157 T S A K D S I N V E Q A F L T
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 N157 T S A L D S T N V E D A F L T
Red Bread Mold Neurospora crassa P33723 203 22458 N157 T S A K N A S N V E Q A F L T
Conservation
Percent
Protein Identity: 100 N.A. 65 46.5 N.A. 79.5 80 N.A. 69.6 73 47.4 65.3 N.A. 44.7 44.2 46.6 52.4
Protein Similarity: 100 N.A. 65.4 62.2 N.A. 82.8 83.3 N.A. 79 80.4 63.3 75.4 N.A. 59.3 61.1 59 68.2
P-Site Identity: 100 N.A. 100 66.6 N.A. 93.3 93.3 N.A. 6.6 13.3 73.3 86.6 N.A. 6.6 0 66.6 60
P-Site Similarity: 100 N.A. 100 80 N.A. 93.3 93.3 N.A. 26.6 33.3 86.6 93.3 N.A. 26.6 33.3 80 80
Percent
Protein Identity: N.A. 40.8 N.A. 41.9 39.8 37.9
Protein Similarity: N.A. 58.1 N.A. 59 58.2 57.6
P-Site Identity: N.A. 6.6 N.A. 0 0 6.6
P-Site Similarity: N.A. 33.3 N.A. 26.6 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 24 53 18 6 0 0 6 0 0 24 36 18 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 0 0 12 36 6 0 0 0 36 6 6 0 0 % D
% Glu: 53 18 0 0 6 12 18 6 0 24 30 59 6 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 6 0 0 24 53 18 % F
% Gly: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % H
% Ile: 6 0 0 0 0 0 12 0 0 6 6 0 0 6 0 % I
% Lys: 6 0 0 18 53 18 0 6 0 0 0 6 0 0 0 % K
% Leu: 0 0 0 6 0 0 0 0 0 0 0 0 0 24 24 % L
% Met: 6 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 6 36 53 18 0 6 0 0 6 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 24 59 24 0 18 53 36 6 0 0 0 6 0 0 % S
% Thr: 24 48 18 0 0 0 6 6 6 0 0 0 6 0 42 % T
% Val: 6 6 0 0 0 6 0 6 24 48 18 0 18 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _