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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 8.79
Human Site: S162 Identified Species: 12.08
UniProt: A6NDJ8 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDJ8 NP_940892 181 20210 S162 G P L F S E K S P D H I Q L N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 S193 G P L F S E K S P D H I Q L N
Dog Lupus familis XP_539883 217 24593 T192 L H L L G E R T L D S P A P D
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 N191 G P M F S E K N T D H I Q L D
Rat Rattus norvegicus Q53B90 210 23211 N191 G P M F S E K N T D H I Q L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977 I136 I E K N P V G I K L D S K D V
Chicken Gallus gallus XP_414313 215 23743 K195 G G P M F S E K N T D S I K L
Frog Xenopus laevis Q32NQ0 213 24055 P190 F H Y H N E S P R N S F I L D
Zebra Danio Brachydanio rerio NP_001038812 208 22961 V188 G P M F T E N V T D S F K L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 V196 D A N N V E E V P E N T I T L
Honey Bee Apis mellifera XP_624576 219 25203 N195 E N R Q I N A N E D E V V R L
Nematode Worm Caenorhab. elegans NP_502576 210 23303 S185 Q G V V E Q G S S G T F Q L G
Sea Urchin Strong. purpuratus XP_794320 208 23436 G189 G E S S L A K G E T S K L S L
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 K183 S Q A A L E R K P S N V V Q M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 S183 Q T N A N K T S G P G T V Q M
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 Q183 Q N L N E T T Q K K E D K G N
Red Bread Mold Neurospora crassa P33723 203 22458 K183 S I A T N N T K A S V N V S P
Conservation
Percent
Protein Identity: 100 N.A. 65 46.5 N.A. 79.5 80 N.A. 69.6 73 47.4 65.3 N.A. 44.7 44.2 46.6 52.4
Protein Similarity: 100 N.A. 65.4 62.2 N.A. 82.8 83.3 N.A. 79 80.4 63.3 75.4 N.A. 59.3 61.1 59 68.2
P-Site Identity: 100 N.A. 100 20 N.A. 73.3 73.3 N.A. 0 6.6 13.3 40 N.A. 13.3 6.6 20 13.3
P-Site Similarity: 100 N.A. 100 40 N.A. 93.3 93.3 N.A. 6.6 13.3 33.3 60 N.A. 33.3 20 33.3 13.3
Percent
Protein Identity: N.A. 40.8 N.A. 41.9 39.8 37.9
Protein Similarity: N.A. 58.1 N.A. 59 58.2 57.6
P-Site Identity: N.A. 13.3 N.A. 6.6 13.3 0
P-Site Similarity: N.A. 33.3 N.A. 20 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 12 12 0 6 6 0 6 0 0 0 6 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 0 0 0 0 0 0 42 12 6 0 6 24 % D
% Glu: 6 12 0 0 12 53 12 0 12 6 12 0 0 0 0 % E
% Phe: 6 0 0 30 6 0 0 0 0 0 0 18 0 0 0 % F
% Gly: 42 12 0 0 6 0 12 6 6 6 6 0 0 6 6 % G
% His: 0 12 0 6 0 0 0 0 0 0 24 0 0 0 0 % H
% Ile: 6 6 0 0 6 0 0 6 0 0 0 24 18 0 0 % I
% Lys: 0 0 6 0 0 6 30 18 12 6 0 6 18 6 0 % K
% Leu: 6 0 24 6 12 0 0 0 6 6 0 0 6 42 24 % L
% Met: 0 0 18 6 0 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 0 12 12 18 18 12 6 18 6 6 12 6 0 0 18 % N
% Pro: 0 30 6 0 6 0 0 6 24 6 0 6 0 6 6 % P
% Gln: 18 6 0 6 0 6 0 6 0 0 0 0 30 12 0 % Q
% Arg: 0 0 6 0 0 0 12 0 6 0 0 0 0 6 0 % R
% Ser: 12 0 6 6 24 6 6 24 6 12 24 12 0 12 0 % S
% Thr: 0 6 0 6 6 6 18 6 18 12 6 12 0 6 6 % T
% Val: 0 0 6 6 6 6 0 12 0 0 6 12 24 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _