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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 47.27
Human Site: S59 Identified Species: 65
UniProt: A6NDJ8 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDJ8 NP_940892 181 20210 S59 I T Q S Y Y R S A N G A I L A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 S90 I T Q S Y Y R S A N G A I L A
Dog Lupus familis XP_539883 217 24593 S89 I T Q S Y Y R S A H A A I I A
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 S88 I T Q S Y Y R S A N G A I L A
Rat Rattus norvegicus Q53B90 210 23211 S88 I T Q S Y Y R S A N G A I L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977 A33 Y Y R S A N G A I L A Y D I T
Chicken Gallus gallus XP_414313 215 23743 S92 I T Q S Y Y R S A N G A I L A
Frog Xenopus laevis Q32NQ0 213 24055 S87 I T Q S Y Y R S A H G A I I A
Zebra Danio Brachydanio rerio NP_001038812 208 22961 S85 I T Q S Y Y R S A N G A I I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 S93 I T Q S Y Y R S A N G V L I V
Honey Bee Apis mellifera XP_624576 219 25203 S92 I T Q S Y Y R S A N G V I V V
Nematode Worm Caenorhab. elegans NP_502576 210 23303 S82 I T Q S Y Y R S A N G I V L C
Sea Urchin Strong. purpuratus XP_794320 208 23436 S86 I T Q S Y Y R S A N G V I I A
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 G80 I T S S Y Y R G A H G I I I V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 G80 I T S S Y Y R G A H G I I I V
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 G80 I T S S Y Y R G S H G I I I V
Red Bread Mold Neurospora crassa P33723 203 22458 G80 I T S S Y Y R G A H G I C V V
Conservation
Percent
Protein Identity: 100 N.A. 65 46.5 N.A. 79.5 80 N.A. 69.6 73 47.4 65.3 N.A. 44.7 44.2 46.6 52.4
Protein Similarity: 100 N.A. 65.4 62.2 N.A. 82.8 83.3 N.A. 79 80.4 63.3 75.4 N.A. 59.3 61.1 59 68.2
P-Site Identity: 100 N.A. 100 80 N.A. 100 100 N.A. 6.6 100 86.6 86.6 N.A. 73.3 80 80 86.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 26.6 100 100 93.3 N.A. 86.6 86.6 86.6 93.3
Percent
Protein Identity: N.A. 40.8 N.A. 41.9 39.8 37.9
Protein Similarity: N.A. 58.1 N.A. 59 58.2 57.6
P-Site Identity: N.A. 60 N.A. 60 53.3 53.3
P-Site Similarity: N.A. 73.3 N.A. 73.3 73.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 6 0 0 6 89 0 12 48 0 0 48 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 6 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 6 24 0 0 89 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 % H
% Ile: 95 0 0 0 0 0 0 0 6 0 0 30 77 53 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 6 0 0 6 36 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 6 0 0 0 59 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 71 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 6 0 0 0 95 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 24 100 0 0 0 71 6 0 0 0 0 0 0 % S
% Thr: 0 95 0 0 0 0 0 0 0 0 0 0 0 0 12 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 18 6 12 36 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 6 0 0 95 95 0 0 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _