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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 55.45
Human Site: S74 Identified Species: 76.25
UniProt: A6NDJ8 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDJ8 NP_940892 181 20210 S74 Y D I T K R S S F L S V P H W
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 S105 Y D I T K R S S F L S V P H W
Dog Lupus familis XP_539883 217 24593 T104 Y D L T R R S T F E S V P H W
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 T103 Y D I S K R S T F L S V P H W
Rat Rattus norvegicus Q53B90 210 23211 T103 Y D I S K R S T F L S V P H W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977 I48 K K G S F L S I P Y W I E D V
Chicken Gallus gallus XP_414313 215 23743 S107 Y D I S K R G S F L S I P R W
Frog Xenopus laevis Q32NQ0 213 24055 S102 Y D I T R R Q S F E S V P H W
Zebra Danio Brachydanio rerio NP_001038812 208 22961 T100 Y D I T K K A T F L S V P K W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 S108 Y D I T K R S S F S N L Q K W
Honey Bee Apis mellifera XP_624576 219 25203 T107 Y D I T K R S T F L S L Q H W
Nematode Worm Caenorhab. elegans NP_502576 210 23303 S97 Y D I T C K Q S F G S L Q R W
Sea Urchin Strong. purpuratus XP_794320 208 23436 T101 Y D I T K K E T F C N V P R W
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 S95 Y D I T D M E S F N N V K Q W
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 S95 Y D C T E M E S F N N V K Q W
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 S95 Y D V T D Q E S F N G V K M W
Red Bread Mold Neurospora crassa P33723 203 22458 S95 Y D V T D M D S F N N V K Q W
Conservation
Percent
Protein Identity: 100 N.A. 65 46.5 N.A. 79.5 80 N.A. 69.6 73 47.4 65.3 N.A. 44.7 44.2 46.6 52.4
Protein Similarity: 100 N.A. 65.4 62.2 N.A. 82.8 83.3 N.A. 79 80.4 63.3 75.4 N.A. 59.3 61.1 59 68.2
P-Site Identity: 100 N.A. 100 73.3 N.A. 86.6 86.6 N.A. 6.6 73.3 80 73.3 N.A. 66.6 80 53.3 60
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. 20 86.6 86.6 93.3 N.A. 80 93.3 66.6 80
Percent
Protein Identity: N.A. 40.8 N.A. 41.9 39.8 37.9
Protein Similarity: N.A. 58.1 N.A. 59 58.2 57.6
P-Site Identity: N.A. 53.3 N.A. 46.6 46.6 46.6
P-Site Similarity: N.A. 60 N.A. 60 60 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 6 0 6 0 0 0 0 6 0 0 0 0 0 % C
% Asp: 0 95 0 0 18 0 6 0 0 0 0 0 0 6 0 % D
% Glu: 0 0 0 0 6 0 24 0 0 12 0 0 6 0 0 % E
% Phe: 0 0 0 0 6 0 0 0 95 0 0 0 0 0 0 % F
% Gly: 0 0 6 0 0 0 6 0 0 6 6 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 42 0 % H
% Ile: 0 0 71 0 0 0 0 6 0 0 0 12 0 0 0 % I
% Lys: 6 6 0 0 53 18 0 0 0 0 0 0 24 12 0 % K
% Leu: 0 0 6 0 0 6 0 0 0 42 0 18 0 0 0 % L
% Met: 0 0 0 0 0 18 0 0 0 0 0 0 0 6 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 24 30 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 6 0 0 0 53 0 0 % P
% Gln: 0 0 0 0 0 6 12 0 0 0 0 0 18 18 0 % Q
% Arg: 0 0 0 0 12 53 0 0 0 0 0 0 0 18 0 % R
% Ser: 0 0 0 24 0 0 48 59 0 6 59 0 0 0 0 % S
% Thr: 0 0 0 77 0 0 0 36 0 0 0 0 0 0 0 % T
% Val: 0 0 12 0 0 0 0 0 0 0 0 71 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 95 % W
% Tyr: 95 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _