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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 52.12
Human Site: Y88 Identified Species: 71.67
UniProt: A6NDJ8 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDJ8 NP_940892 181 20210 Y88 W I E D V R K Y A G S N I V Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094209 269 29623 Y119 W I E D V R K Y A G S N I V Q
Dog Lupus familis XP_539883 217 24593 Y118 W I H E I E K Y G A A N L V I
Cat Felis silvestris
Mouse Mus musculus Q8CG50 210 23245 Y117 W I E D V R K Y A G S N I V Q
Rat Rattus norvegicus Q53B90 210 23211 Y117 W I E D V R K Y A G S N I V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505416 151 16977 N62 V R K Y A G S N I V Q L L I G
Chicken Gallus gallus XP_414313 215 23743 Y121 W I E D V R K Y A G S N I V Q
Frog Xenopus laevis Q32NQ0 213 24055 Y116 W I Y E A G K Y G A A N L M L
Zebra Danio Brachydanio rerio NP_001038812 208 22961 Y114 W M E D V K K Y G G S N I V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523970 219 25031 Y122 W I E E V R R Y T A S N V L I
Honey Bee Apis mellifera XP_624576 219 25203 Y121 W V E E V R R Y T S S H V L L
Nematode Worm Caenorhab. elegans NP_502576 210 23303 F111 W I D D V S K F A A P N V V K
Sea Urchin Strong. purpuratus XP_794320 208 23436 Y115 W I E D V Q K Y A G G S V I C
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 Y109 W L D E I D R Y A N D S V R K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZRE2 205 22706 Y109 W L S E I D R Y A N E S V C K
Baker's Yeast Sacchar. cerevisiae P01123 206 23196 Y109 W L Q E I D R Y A T S T V L K
Red Bread Mold Neurospora crassa P33723 203 22458 Y109 W L Q E I D R Y A T E G V N K
Conservation
Percent
Protein Identity: 100 N.A. 65 46.5 N.A. 79.5 80 N.A. 69.6 73 47.4 65.3 N.A. 44.7 44.2 46.6 52.4
Protein Similarity: 100 N.A. 65.4 62.2 N.A. 82.8 83.3 N.A. 79 80.4 63.3 75.4 N.A. 59.3 61.1 59 68.2
P-Site Identity: 100 N.A. 100 40 N.A. 100 100 N.A. 0 100 33.3 73.3 N.A. 53.3 40 53.3 60
P-Site Similarity: 100 N.A. 100 66.6 N.A. 100 100 N.A. 20 100 60 86.6 N.A. 80 80 80 86.6
Percent
Protein Identity: N.A. 40.8 N.A. 41.9 39.8 37.9
Protein Similarity: N.A. 58.1 N.A. 59 58.2 57.6
P-Site Identity: N.A. 20 N.A. 20 26.6 20
P-Site Similarity: N.A. 73.3 N.A. 66.6 80 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 0 0 65 24 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 % C
% Asp: 0 0 12 48 0 24 0 0 0 0 6 0 0 0 0 % D
% Glu: 0 0 53 48 0 6 0 0 0 0 12 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 12 0 0 18 42 6 6 0 0 6 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 6 0 0 0 % H
% Ile: 0 59 0 0 30 0 0 0 6 0 0 0 36 12 12 % I
% Lys: 0 0 6 0 0 6 59 0 0 0 0 0 0 0 30 % K
% Leu: 0 24 0 0 0 0 0 0 0 0 0 6 18 18 12 % L
% Met: 0 6 0 0 0 0 0 0 0 0 0 0 0 6 0 % M
% Asn: 0 0 0 0 0 0 0 6 0 12 0 59 0 6 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 6 0 0 0 6 % P
% Gln: 0 0 12 0 0 6 0 0 0 0 6 0 0 0 30 % Q
% Arg: 0 6 0 0 0 42 36 0 0 0 0 0 0 6 0 % R
% Ser: 0 0 6 0 0 6 6 0 0 6 53 18 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 12 12 0 6 0 0 0 % T
% Val: 6 6 0 0 59 0 0 0 0 6 0 0 48 48 0 % V
% Trp: 95 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 6 0 0 0 89 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _