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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 0.91
Human Site: S188 Identified Species: 2.5
UniProt: A6NDL7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDL7 NP_001010977 271 31188 S188 D T N F P R S S N N F D Y I L
Chimpanzee Pan troglodytes XP_001151722 264 29530 A192 F Y Y D Y V L A S D V V Y H H
Rhesus Macaque Macaca mulatta XP_001096385 251 28899 P184 A D V V Y A H P F L E E L L I
Dog Lupus familis XP_854388 243 27627 P176 A D V V Y A H P F L E E L L I
Cat Felis silvestris
Mouse Mus musculus Q8CDZ2 244 28049 P177 A D V V Y A H P F L E E L L M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513413 242 27299 P175 A D V V Y A H P F L D E L L A
Chicken Gallus gallus XP_001232407 265 30152 V187 Y I M A A D V V Y H H P F L D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5BLD8 218 24426 T151 D I V Y L E E T F P A L L Q T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781765 199 22589 I132 D I I L G A D I I Y I E D T F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.9 90.4 77.8 N.A. 78.5 N.A. N.A. 64.9 65.3 N.A. 32.4 N.A. N.A. N.A. N.A. 31
Protein Similarity: 100 60.1 91.5 82.2 N.A. 82.6 N.A. N.A. 77.4 78.5 N.A. 49.8 N.A. N.A. N.A. N.A. 43.9
P-Site Identity: 100 6.6 0 0 N.A. 0 N.A. N.A. 0 0 N.A. 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 26.6 20 20 N.A. 20 N.A. N.A. 13.3 20 N.A. 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 0 0 12 12 56 0 12 0 0 12 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 45 0 12 0 12 12 0 0 12 12 12 12 0 12 % D
% Glu: 0 0 0 0 0 12 12 0 0 0 34 56 0 0 0 % E
% Phe: 12 0 0 12 0 0 0 0 56 0 12 0 12 0 12 % F
% Gly: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 45 0 0 12 12 0 0 12 12 % H
% Ile: 0 34 12 0 0 0 0 12 12 0 12 0 0 12 23 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 12 12 0 12 0 0 45 0 12 56 56 12 % L
% Met: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 12 0 0 0 0 0 12 12 0 0 0 0 0 % N
% Pro: 0 0 0 0 12 0 0 45 0 12 0 12 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % Q
% Arg: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 12 12 12 0 0 0 0 0 0 % S
% Thr: 0 12 0 0 0 0 0 12 0 0 0 0 0 12 12 % T
% Val: 0 0 56 45 0 12 12 12 0 0 12 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 12 12 12 56 0 0 0 12 12 0 0 23 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _