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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 3.94
Human Site: Y261 Identified Species: 10.83
UniProt: A6NDL7 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NDL7 NP_001010977 271 31188 Y261 P S L N I K L Y K A V K K N R
Chimpanzee Pan troglodytes XP_001151722 264 29530 E251 T L L A E Y P E S S V K L F K
Rhesus Macaque Macaca mulatta XP_001096385 251 28899 K242 S L N I K L Y K A V K K N R R
Dog Lupus familis XP_854388 243 27627 K234 S L N I K L Y K A M K K S R R
Cat Felis silvestris
Mouse Mus musculus Q8CDZ2 244 28049 K235 S L N I K L Y K A M K K N R R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513413 242 27299 K233 S W S I K L Y K A V K I N G K
Chicken Gallus gallus XP_001232407 265 30152 Y248 P S L N I T L Y K A M R K G R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5BLD8 218 24426 A209 R D I H V Y R A V K N K S N T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781765 199 22589 G190 V L H D S E R G I E I Y S A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 40.9 90.4 77.8 N.A. 78.5 N.A. N.A. 64.9 65.3 N.A. 32.4 N.A. N.A. N.A. N.A. 31
Protein Similarity: 100 60.1 91.5 82.2 N.A. 82.6 N.A. N.A. 77.4 78.5 N.A. 49.8 N.A. N.A. N.A. N.A. 43.9
P-Site Identity: 100 20 13.3 13.3 N.A. 13.3 N.A. N.A. 0 73.3 N.A. 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 33.3 13.3 13.3 N.A. 13.3 N.A. N.A. 6.6 86.6 N.A. 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 12 45 23 0 0 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 12 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 12 12 0 12 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 0 0 0 0 0 0 12 0 0 0 0 0 23 0 % G
% His: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 45 23 0 0 0 12 0 12 12 0 0 0 % I
% Lys: 0 0 0 0 45 12 0 45 23 12 45 67 23 0 34 % K
% Leu: 0 56 34 0 0 45 23 0 0 0 0 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 23 12 0 0 0 0 % M
% Asn: 0 0 34 23 0 0 0 0 0 0 12 0 34 23 0 % N
% Pro: 23 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 12 0 0 0 0 0 23 0 0 0 0 12 0 34 56 % R
% Ser: 45 23 12 0 12 0 0 0 12 12 0 0 34 0 0 % S
% Thr: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 12 % T
% Val: 12 0 0 0 12 0 0 0 12 23 23 0 0 0 0 % V
% Trp: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 23 45 23 0 0 0 12 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _