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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPEPPSL1 All Species: 12.73
Human Site: Y464 Identified Species: 56
UniProt: A6NEC2 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NEC2 NP_006301 478 53747 Y464 F K K G M N M Y L T K F Q Q K
Chimpanzee Pan troglodytes XP_001152327 663 73663 Y648 F K K G M N M Y L T K F Q Q K
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q11011 920 103333 Y465 F K K G M N M Y L T K F Q Q K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001157499 872 98035 P640 F I R D L F T P I G M K L G W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728615 1053 120270 Y605 F R K G M N L Y L T R H Q Y G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188563 781 87435 I757 V Q Q S L E N I R L K A K W L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.4 N.A. N.A. N.A. 49.7 N.A. N.A. N.A. N.A. N.A. 43.5 N.A. 29.5 N.A. N.A. 39.5
Protein Similarity: 100 70.5 N.A. N.A. N.A. 50.5 N.A. N.A. N.A. N.A. N.A. 46.5 N.A. 34.9 N.A. N.A. 45.3
P-Site Identity: 100 100 N.A. N.A. N.A. 100 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. 60 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. N.A. N.A. 100 N.A. N.A. N.A. N.A. N.A. 26.6 N.A. 80 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % E
% Phe: 84 0 0 0 0 17 0 0 0 0 0 50 0 0 0 % F
% Gly: 0 0 0 67 0 0 0 0 0 17 0 0 0 17 17 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % H
% Ile: 0 17 0 0 0 0 0 17 17 0 0 0 0 0 0 % I
% Lys: 0 50 67 0 0 0 0 0 0 0 67 17 17 0 50 % K
% Leu: 0 0 0 0 34 0 17 0 67 17 0 0 17 0 17 % L
% Met: 0 0 0 0 67 0 50 0 0 0 17 0 0 0 0 % M
% Asn: 0 0 0 0 0 67 17 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % P
% Gln: 0 17 17 0 0 0 0 0 0 0 0 0 67 50 0 % Q
% Arg: 0 17 17 0 0 0 0 0 17 0 17 0 0 0 0 % R
% Ser: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 17 0 0 67 0 0 0 0 0 % T
% Val: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 17 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _