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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARRDC5 All Species: 24.85
Human Site: T108 Identified Species: 60.74
UniProt: A6NEK1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A6NEK1 NP_001073992 328 36841 T108 L P P R L P S T F T S K F G H
Chimpanzee Pan troglodytes XP_001140793 342 38272 T122 L P P R L P S T F T S K F G H
Rhesus Macaque Macaca mulatta XP_001085880 175 19460
Dog Lupus familis XP_533947 328 36536 T108 L P P R L P S T F T S K I G H
Cat Felis silvestris
Mouse Mus musculus Q497K5 325 36770 T108 L P P R L P S T F N S K I G H
Rat Rattus norvegicus NP_001102878 325 36661 T108 L P P R L P S T F N S K I G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521751 159 17941
Chicken Gallus gallus XP_413881 472 50694 T183 L P Q E P L V T S F T G K Y G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649688 422 45988 S116 L P P N L P S S F E G E F G H
Honey Bee Apis mellifera XP_001121347 409 46672 S116 L P H N I P S S F E H K Y G H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 48.4 82.9 N.A. 70.4 72.2 N.A. 21 20.3 N.A. N.A. N.A. 22 20.2 N.A. N.A.
Protein Similarity: 100 94.7 51.8 90.5 N.A. 80.7 82 N.A. 32.9 36 N.A. N.A. N.A. 38.8 38.1 N.A. N.A.
P-Site Identity: 100 100 0 93.3 N.A. 86.6 86.6 N.A. 0 20 N.A. N.A. N.A. 66.6 53.3 N.A. N.A.
P-Site Similarity: 100 100 0 93.3 N.A. 86.6 86.6 N.A. 0 26.6 N.A. N.A. N.A. 80 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 20 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 70 10 0 0 30 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 10 0 70 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 70 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 30 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 60 10 0 0 % K
% Leu: 80 0 0 0 60 10 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 0 0 0 0 0 20 0 0 0 0 0 % N
% Pro: 0 80 60 0 10 70 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 70 20 10 0 50 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 60 0 30 10 0 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _