KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARRDC5
All Species:
13.64
Human Site:
T222
Identified Species:
33.33
UniProt:
A6NEK1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A6NEK1
NP_001073992
328
36841
T222
H
I
Q
Y
E
G
F
T
P
S
A
E
R
R
S
Chimpanzee
Pan troglodytes
XP_001140793
342
38272
M236
H
I
Q
Y
E
G
F
M
P
S
A
E
R
R
S
Rhesus Macaque
Macaca mulatta
XP_001085880
175
19460
R75
F
T
P
G
A
E
R
R
S
R
L
D
S
S
E
Dog
Lupus familis
XP_533947
328
36536
T222
H
V
Q
Y
E
G
F
T
P
N
A
E
R
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q497K5
325
36770
T222
H
V
Q
Y
E
G
F
T
P
S
A
E
R
R
R
Rat
Rattus norvegicus
NP_001102878
325
36661
T222
H
V
Q
Y
E
G
F
T
P
S
A
E
R
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521751
159
17941
L59
L
T
S
M
S
C
T
L
N
S
Y
V
T
Y
E
Chicken
Gallus gallus
XP_413881
472
50694
K297
Q
T
Y
L
A
S
G
K
T
K
T
F
R
Q
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649688
422
45988
Q230
L
V
T
F
H
T
N
Q
P
R
S
E
K
R
E
Honey Bee
Apis mellifera
XP_001121347
409
46672
S230
Q
K
L
K
F
Y
A
S
T
P
H
T
R
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.1
48.4
82.9
N.A.
70.4
72.2
N.A.
21
20.3
N.A.
N.A.
N.A.
22
20.2
N.A.
N.A.
Protein Similarity:
100
94.7
51.8
90.5
N.A.
80.7
82
N.A.
32.9
36
N.A.
N.A.
N.A.
38.8
38.1
N.A.
N.A.
P-Site Identity:
100
93.3
0
86.6
N.A.
86.6
86.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
6.6
100
N.A.
93.3
93.3
N.A.
6.6
13.3
N.A.
N.A.
N.A.
46.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
10
0
0
0
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
50
10
0
0
0
0
0
60
0
0
30
% E
% Phe:
10
0
0
10
10
0
50
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
10
0
50
10
0
0
0
0
0
0
0
0
% G
% His:
50
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
0
0
0
10
0
10
0
0
10
0
10
% K
% Leu:
20
0
10
10
0
0
0
10
0
0
10
0
0
10
0
% L
% Met:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
60
10
0
0
0
0
0
% P
% Gln:
20
0
50
0
0
0
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
20
0
0
70
60
20
% R
% Ser:
0
0
10
0
10
10
0
10
10
50
10
0
10
10
30
% S
% Thr:
0
30
10
0
0
10
10
40
20
0
10
10
10
0
0
% T
% Val:
0
40
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
50
0
10
0
0
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _